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PhaseII study of Nab-paclitaxel followed by EC as neoadjuvant chemotherapy for the operable breast cancer

Phase 2
Conditions
Breast cancer
Registration Number
JPRN-UMIN000022931
Lead Sponsor
Rakuwakai Otowa Hospital Breast oncology department
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Complete: follow-up complete
Sex
Female
Target Recruitment
24
Inclusion Criteria

Not provided

Exclusion Criteria

1) History of hypersensitivity reaction 2) Active double cander 3) Other severe complications, such as infections, diarrhea, uncontrolled angina, myocardial infarction within 6 months, heart failure. 4) Case of contraindication of this drug 5) Patients with peripheral nerve symptoms 6) Pregnant or lactating women, women who are capable of pregnancy, intend to get pregnant 7) Judged ineligible based on physicians' decision

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Pathological complete response rate
Secondary Outcome Measures
NameTimeMethod
Response rate, rate of breast conserving surgery, frequency and degree of adverse events, remains rate of peripheral neuropathy, QOL survey, Correlation of the QOL survey results and the pCR rate and the response rate
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