Effect of Blood Transfusions on the Outcome of Low Birth Weight Preterm Infants
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Red Blood Cells
- Sponsor
- Kasr El Aini Hospital
- Enrollment
- 40
- Primary Endpoint
- Change in heart rate
- Last Updated
- 4 years ago
Overview
Brief Summary
A cross sectional study to assess the effect of blood transfusions on the outcome of preterm infants
Detailed Description
This is a cross sectional study carried on preterm infants who are staying in the hospital as "growers"; to gain weight. We will assess blood transfusion received by these preterm infants in details.
Investigators
Douaa El Saied El Sherbiny
Lecturer of Pediatrics, Cairo university
Kasr El Aini Hospital
Eligibility Criteria
Inclusion Criteria
- •Grower preterm infants
Exclusion Criteria
- •Severe illness, Hypovolemic shock, Hypoxia, Oxygen therapy, Surgical intervention
Outcomes
Primary Outcomes
Change in heart rate
Time Frame: immediately before and immediately after blood transfusion
Heart rate per minute
Change in respiratory rate
Time Frame: immediately before and immediately after blood transfusion
Respiratory rate per minute
Change in hemoglobin
Time Frame: immediately before and immediately after blood transfusion
Hemoglobin in grams/dl
Change in weight gain
Time Frame: within 4 days before and within 4 days after blood transfusion
Average weight gain in grams/kg/day
Change in hematocrit value
Time Frame: immediately before and immediately after blood transfusion
Hematocrit value percentage
Secondary Outcomes
- Metabolic acidosis(in the previous 24 hours before blood transfusion)
- Apnea and bradycardia(in the previous 24 hours before blood transfusion)
- Length of stay in the NICU(from date of birth until the date of transfer to the "grower ward" or date of death from any cause, whichever came first, assessed up to 3 months.)
- Acute blood loss(in the previous 24 hours before blood transfusion)
- Doubling of oxygen requirements(in the previous 2 days before blood transfusion)
- Mortality(from the date of transfer to grower ward, assessed up to 3 months.)
- Mechanical ventilation(in the previous 24 hours before blood transfusion)
- Supplemental oxygen(in the previous 24 hours before blood transfusion)
- Tachypnea(in the previous 24 hours before blood transfusion)
- Length of stay in the hospital(from date of birth until the date of discharge home or date of death from any cause, whichever came first, assessed up to 3 months.)
- Tachycardia(in the previous 24 hours before blood transfusion)
- Poor weight gain(in the previous 4 days before blood transfusion)