The Follow up of Chinese Young Children With Melamine-Related-Calculus
- Conditions
- Calculus
- Registration Number
- NCT00895765
- Lead Sponsor
- Zhejiang University
- Brief Summary
The purpose of this study is to investigate the lesions, clinical features and outcome in young children with melamine-related-calculus.
- Detailed Description
1. To investigate the outcome of melamine-related-calculus.
* The change of calculus.
* The change of obstruction features,including hydronephrosis and ureterectasia.
* The change of the urinalysis.
2. To investigate the change of renal function in children with melamine-related-calculus during the follow up.
* Creatinine, urea and uric acid.
* α and β2 microglobulin.
3. To analysis the factors might be associated with the outcome.
* The characteristics of patients: age, gender, and so on.
* The characteristics of calculus: location, size, and so on.
Recruitment & Eligibility
- Status
- UNKNOWN
- Sex
- All
- Target Recruitment
- 250
- children with melamine-related-calculus: with a history of melamine contaminated products
- the parents leave the detailed information for contact and willing to be recalled
- children with other congenital renal abnormality
- children with hypercalciuria
- children have abnormality of parathyroid gland
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method The calculus measured by sonography at 1, 3, 6 and 12 months
- Secondary Outcome Measures
Name Time Method Renal function (e.g., creatinine, microglobulin) at 1, 3, 6 and 12 months
Trial Locations
- Locations (1)
The Children's Hospital of Zhejiang University School of Medicine
🇨🇳Hangzhou, Zhejiang, China