Is endoscopic therapy with oral medicine better than endoscopic therapy alone to prevent further episodes of hemetemesis (blood in vomitus) in children with portal hypertensio

Not Applicable

• Conditions: Health Condition 1: K766- Portal hypertension

• Registration Number: CTRI/2020/08/026982
• Lead Sponsor: Sanjay Gandhi Postgraduate Institute of Medical Sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 17 October 2022

Recruitment & Eligibility

• Status: Open to Recruitment
• Sex: Not specified
• Target Recruitment: 0

Inclusion Criteria

All children of age 3-18 years with portal hypertension with a prior history of oesophageal variceal bleed

Exclusion Criteria

Previously underwent endoscopic band ligation or sclerotherapy

Large gastric varix (F3 varix)

Contraindications to the use of beta blockers

Previous shunt surgery

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Rate of rebleeding in children with portal hypertension receiving secondary prophylaxis with EVL alone versus EVL with beta blockersTimepoint: Early: Rebleeding occurring before variceal eradication. <br/ ><br>Late: Rebleeding occurring after variceal eradication till 1 year of follow up.

Secondary Outcome Measures

Name	Time	Method
Compliance with beta blockersTimepoint: Till 1 year;Percentage of children developing complications due to EVL or beta blockersTimepoint: Till 1 year