Analgesic efficacy of ultrasound guided bilateral transversus thoracis muscle plane block in pediatric cardiac surgery
Phase 1
- Conditions
- PaediatricsAnaesthesia
- Registration Number
- PACTR201910859535009
- Lead Sponsor
- Mansoura university children hospital
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 80
Inclusion Criteria
1.Age 2 to 12 years.
2.Scheduled for elective cardiac surgery.
3.Via median sternotomy.
4. Congenital simple left to right intra cardiac shunt
Exclusion Criteria
1.Refusal patients guardians.
2.Redo cardiac surgery.
3.Local infection of the skin and subcutaneous tissue at the site of needle puncture
4. Hypersensitivity to local anesthetics.
5. Coagulation disorders.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method 1- Total dose of intra operative fentanyl requirements.<br>2- Post operative pain that will be assessed at 1h, 2h, 6h, 12h, 18, 24 after extubation, and will be managed according to objective pain discomfort score(OPDS) in children.<br>
- Secondary Outcome Measures
Name Time Method 1-Heart rate [HR] and invasive mean arterial blood pressure [MAP] will be recorded; before induction of anesthesia (basal value), after induction of anesthesia, after skin incision, after sternotomy, 15 min after CPB and after the closure of sternum. <br>2- Total dose of intra operative fentanyl requirements(ug/kg).<br>3- Aortic cross clamping time (minutes).<br>4- Cardiopulmonary bypass time (minutes).<br>5-The number of patients who will be extubated in operating room (within 15 minutes of the end of surgery) were recorded.<br>6- Time to extubation (hours). <br>7- Post extubation PaO2, PaCO2 will be assessed each 3 hour for 24 hours.<br>8-Time of first rescue analgesia <br>9- Total dose of morphine consumption in the first 24 postoperative hours. <br>10- Intensive care unit (ICU) length of stay. <br>11- Postoperative complications (the need for re-intubation, nausea and vomiting, pruritus, respiratory depression and neurological deficits) will be reported<br>