The effect of sea buckthorn on clinical symptoms of rheumatoid arthritis

Phase 3

• Conditions: Rheumatoid arthritis.; Rheumatoid arthritis with rheumatoid factor

• Registration Number: IRCT20210630051742N1
• Lead Sponsor: Mashhad University of Medical Sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 29 November 2021

Recruitment & Eligibility

• Status: Pending
• Sex: All
• Target Recruitment: 30

Inclusion Criteria

Newly diagnosed patient based on ACR/EULAER criteria for rheumatoid arthritis.
Patient who has received no medication for rheumatoid arthritis until now.
Disease severity should be between 2.5 to 5.5 based on DAS criteria.

Exclusion Criteria

Patient MI history
Patient has hyperlipidemia
Patient has liver or kidney impaired function.
Patient has any neoplasm
Patient has psychiatric diseases.
There is active infection in patient's body.
Patient takes vitamin/mineral supplements.
Patient takes medications like thyroid hormones, Anti hypertensives, contraceptives, diuretics and beta-blockers.
Patient drinks alcohol or smokes.
Patient has any allergy to sea buckthorn.
Patient is pregnant or breastfeeds.
Disease severity is above 5.5 based on DAS criteria.

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Severity of pain. Timepoint: before intervention and 30, 45, 90 days after intervention. Method of measurement: visual analog scale.;Number of tender joints. Timepoint: before intervention and 30, 45, 90 days after intervention. Method of measurement: Disease Activity Score Calculator for Rheumatoid Arthritis.;Number of swollen joints. Timepoint: before intervention and 30, 45, 90 days after intervention. Method of measurement: Disease Activity Score Calculator for Rheumatoid Arthritis.;ESR. Timepoint: Before intervention and 90 days after intervention. Method of measurement: Blood test.