NL-OMON54579招募中不适用
ational study of inherited platelet function disorders in the Netherlands - Trombocytopathy in the Netherlands / TI
niversitair Medisch Centrum Utrecht0 个研究点目标入组 600 人开始时间: 待定最近更新:
适应症
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 发起方
- 入组人数
- 600
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Observational
入排标准
- 年龄范围
- 0 至 99（—）
入选标准
- •(Suspected) PFD defined according to the following criteria:
- •Congenital or familial thrombocytopenia
- •Chronic thrombocytopenia (>1 year) without proven or suspected acquired cause
- •PFD with proven molecular diagnosis.
- •Abnormal LTA for at least one of the agonists and/or abnormal ATP/ADP ratio
- •(storage pool test)
- •History of bleeding diathesis very suspect of a primary hemostasis function
- •defect with or without prolonged Platelet Function Analyser closure time.
- •Inclusion criteria of control group of VWD patients for bruising pattern
- •Patients younger than 18 years old with Von Willebrand*s disease type 1 or type
- •2 that visit the VCK regularly.
排除标准
- •- Inability to give informed consent or inability of the parents to give
- •informed consent in patients < 16 years of age.
- •- Bleeding diathesis due to an acquired PFD
- •- Bleeding diathesis due to moderate or severe von Willebrand disease (VWF
- •risto < 30%)
- •- Bleeding diathesis due to hemophilia or other disorders of secondary
- •hemostasis or fibrinolysis
- •- Current use of antiplatelet therapy
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