CorEvitas International Adolescent Alopecia Areata (AA) Drug Safety and Effectiveness Registry

Recruitment & Eligibility

Status: Enrolling by invitation

Sex: All

Target Recruitment: 1500

Inclusion Criteria

Inclusion Criteria: To be eligible to participate in this registry, an individual must meet all the following criteria: 1. Has ever been diagnosed with severe AA by a dermatologist or a qualified dermatology provider. 2. Is 12-17 years of age at the time of enrollment. 3. Is willing to provide consent/assent for participation in the registry. 4. Has been prescribed a new commercially available advanced therapy and/or conventional systemic therapy for the treatment of severe AA in adolescents in the context of routine clinical care that is consistent with local prescribing guidelines and/or regulations for the country where the site is located. A new therapy is a medication that the subject has never taken before. 1. At the time of registry enrollment OR 2. Within 6 months prior to registry enrollment In the opinion of the treating provider, is deemed a candidate for treatment with a commercially available advanced therapy and/or conventional systemic therapy for the treatment of severe AA in adolescents but has not received nor is planning to initiate treatment at the time of registry enrollment. Exclusion Criteria: An individual who meets any of the following criteria will be excluded from participation in the registry: 1. Is participating or planning to participate in a blinded clinical trial for any investigational medication. 2. Is unwilling or unable to provide standing height measurements.

Exclusion Criteria

Not provided

Study & Design

Study Type: Observational

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
AA epidemiology, presentation, natural history, management, and outcomes

Secondary Outcome Measures

Name	Time	Method
Percentage of patients with history of comorbidities;Patient reported : Hair Concealment Question;Patient reported : Stressful Life Event;Patient reported : Scalp Hair Assessment;Patient reported :Measures for Eye Irritation & Nail Appearance;Patient reported : Numerical Rating Scale for Nasal irritation;Patient reported : Alopecia Areata Patient Priority Outcomes (AAPPO);Patient reported : Patient Health Questionnaire (PHQ);Patient reported :PROMIS Pediatric Sleep Disturbance 4 a;Patient reported : PROMIS Pediatric Stigma 8a;Patient reported : Grief Assessment;Patient reported : Pubertal Tanner Staging;Physician reported : Pubertal Progression: Tanner Staging Assessment;Physician reported : Severity of Alopecia Tool (SALT);Physician reported : Alopecia Areata Investigator Global Assessment Scale (AA-IGA);Physician reported : Measures for Eyebrow & Eyelash Hair loss and Nail Appearance