A comparative clinical study on the combined effect of Ashtachurna and Kushmanda Rasayana in children with mild to moderate malnutrition
试验速览
- 阶段
- 2/3 期
- 状态
- 尚未招募
- 发起方
- Self
- 入组人数
- 40
- 试验地点
- 1
- 主要终点
- To compare the efficacy of Astachurna and Kushmanda rasayana on clinical features, weight, chest circumference, mid arm circumference, mid-thigh circumference, BMI and skin fold thickness in children with mild to moderate malnutrition.
研究概览
简要总结
Malnutrition is a general umbrella term which addresses 3 broad groups like undernutrition, micronutrient related malnutrition and overweight. The term malnutrition addresses undernutrition, which includes wasting (low weight-for-height), stunting (low height-for-age) and underweight (low weight-for-age), Undernutrition impairs the immune function, which leads to growth retardation and impaired psychosocial and cognitive development in children.According to National Family Health Survey -5 (NFHS-5) carried out in 2019 – 2021, 35.5% and 19.3 % India’s children under 5 years are stunted and wasted respectively. 32.1% children under 5 years are underweight in India. In Karnataka, 11% and 5% children are malnourished and acutely malnourished.
Undernutrition in contemporary science resembles the clinical features of Karshya, in Ayurveda. Intake of faulty food habits like fast foods and nutrient poor foods like pizzas, burgers, carbonated drinks and chocolates which are commonly found in children. Clinical manifestation of Karshya are presence of Shushka Sphik, Udara and Greeva (emaciation of buttocks, abdomen and neck), Dhamanijala santata (Prominent venous network in the body), Twagasthishisha (remained with skin and bones), Sthoola parva (prominent inter-phalangeal joints).Karshya is vata pradhana vyadhi , so Brihmana is a choice of treatment which gives Bala, Pushti and reduces Ruksha Guna of *Vata.*But when Agni is not good, Brimhana will not be effective as it affects digestion and absorption majorly. So the study hoypthesis that giving carmonative poly herbal drug along with nutritional supplement is more effective than giving nutritional supplement.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 盲法
- None
入排标准
- 年龄范围
- 3.00 Year(s) 至 12.00 Year(s)(—)
- 性别
- All
入选标准
- •Subjects aged between 3 to 12 years of age, irrespective of gender, religion and socio-economic status.
- •Subjects who fulfill the assessment criteria of mild to moderate Malnutrition as per IAP (Grade I & II) 3)Subjects whose parents/guardian are willing to give the informed assent.
排除标准
- •Subjects with congenital and genetic abnormalities which interferes with nutritional status of the child.
- •Known cases of any systemic and infectious disorders necessitating continuous medications.
结局指标
主要结局
To compare the efficacy of Astachurna and Kushmanda rasayana on clinical features, weight, chest circumference, mid arm circumference, mid-thigh circumference, BMI and skin fold thickness in children with mild to moderate malnutrition.
时间窗: 0th day | 4th week | 8th week | 12th week
次要结局
- 1 To evaluate the efficacy of Kushmanda Rasayana on clinical features, weight, chest circumference, mid arm circumference, mid-thigh circumference, BMI and skin fold thickness in children with mild to moderate malnutrition.(2 To evaluate the efficacy of astachurna and Kushmanda Rasayana on clinical features, weight, chest circumference, mid arm circumference, mid-thigh circumference, BMI and skin fold thickness in children with mild to moderate malnutrition.)
研究者
Dr Suneeta Tammanni Bandigani
JSS Ayurveda Medical College and Hospital
