Impact of Intraoperative Spraying Methylene Blue In Thyroidectomy
试验速览
- 阶段
- 不适用
- 发起方
- 入组人数
- 40
- 主要终点
- Presence of residual or recurrence
研究概览
简要总结
Impact of Intraoperative Spraying methylene blue In thyroidectomy
详细描述
General anaesthesia ,supine position with hyperextension to the neck Low collar incision to the neck , incision to the skin and platysma muscle and fascia ,upper and lower flaps are developed ,separation of strap muscles and identification of the thyroid gland after freeing of investing fascia Ligation of the middle thyroid vein and ligation and separation of the superior pedicle away from the external laryngeal nerve At this point of operation and before ligation of inferior pedicle, methylene blue 0.05% spraying is applied to the field the amount varies according to size of the thyroid lobe and variation in population and neck size Thyroid gland stained by bluish color , recurrent laryngeal nerve not stained or minimally stained so we can avoid injury to it parathyroid glands get red of the stain after about 3 minutes so we can avoid injury to it thyroid gland lose its stain in about 15 minutes so we can remove any residual and decrease residual tissue or recurrence
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 15 Years 至 80 Years(Child, Adult, Older Adult)
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Both sexes
- •Age more than 15 years
- •All pathologies need surgery eg. (mutinodular goiter, malignancy , thyroid nodule,.....etc
- •Total thyroidectomy
排除标准
- •Pregnant females
- •Previous neck surgery or recurrent thyroid surgery
- •Subtotal or partial thyroidectomy
- •Age less than 15 years
- •Preoperative affection to vocal cord
- •Preoperative hypocalcaemia
结局指标
主要结局
Presence of residual or recurrence
时间窗: 3 months
Recurrent laryngeal nerve injury
时间窗: 2 weeks
Operative time
时间窗: 1 day
Intraoperative injury to trachea
时间窗: 2 weeks
Parathyroid gland Injuries
时间窗: 3 months
次要结局
- Stridor(3 months)
- Hypoparathyroidism(3 months)
- Hoarseness of voice(3 months)
- Hypocalcaemia(3 months)
研究者
Mohamed Ahmed Orabi
specialist of Surgical Oncology
Qena Oncology Center
