A Multi-omics-based Metabolic Typing Study of Gastric Cancer
- Conditions
- Gastric CancerMulti-omicsDiagnosis
- Interventions
- Other: Without any intervention
- Registration Number
- NCT06134011
- Lead Sponsor
- Zhejiang Cancer Hospital
- Brief Summary
In the study, the investigators obtained gastric cancer tissues from 480 gastric cancer patients who had undergone surgery at the Zhejiang Cancer Hospital's biospecimen bank between 2012-2019, and obtained relevant clinical information. The gastric cancer tissues were subjected to transcriptomic, metabolomic and other multi-omics testing, and analyzed for the metabolic changes of gastric cancer, and proposed to discover relevant therapeutic targets.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ACTIVE_NOT_RECRUITING
- Sex
- All
- Target Recruitment
- 480
- 18≤age≤80
- Histologically or cytologically confirmed gastric cancer
- Undergo surgery for radical or palliative gastric cancer (both open and laparoscopic)
- Patients with survival follow-up information
- Two or more kinds of malignant tumors at the same time
- Incomplete or missing case information
- Preoperative diagnosis of residual gastric cancer
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Arm && Interventions
Group Intervention Description Cancer tissues Without any intervention - Normal adjacent tissues Without any intervention -
- Primary Outcome Measures
Name Time Method The differences of the metabolism information through study completion, an average of 6 months The differences of the metabolism information between gastric cancer tissues and non-cancerous gastric cancer tissues. These data included Metabolizing enzyme mRNA expression and metabolite content.
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
Cancer Hospital of the University of Chinese Academy of Sciences (Zhejiang Cancer Hospital)
🇨🇳Hangzhou, Zhejiang, China