Evaluation the effect of vitamin D3 in improvement clinical parameters of patients with chronic periodontitis-clinical trial

Phase 4

• Conditions: K05.3; Chronic periodontitis.; Chronic periodontitis

• Registration Number: IRCT20221212056786N3
• Lead Sponsor: Yazd University of Medical Sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 13 November 2023

Recruitment & Eligibility

• Status: Pending
• Sex: Female
• Target Recruitment: 32

Inclusion Criteria

female
Has at least 20 teeth
Blood vitamin D levels below 30 ng/ml (normal level is = 30 ng/ml).
Healthy
Between 30 and 45 years

Exclusion Criteria

Recent antibiotic therapy
Taking vitamin D supplements
Use of corticosteroids or immunosuppressive drugs
Taking aspirin tablets
NSAID use
Taking bisphosphonates or hormone therapy
Patients who were in menopause or pregnancy
Bone diseases
Patient with history of infective endocarditis, congenital problem or acquired heart defects
Immunodeficiency
History of diabetes
Calcium deficiency
Other systemic conditions that may affect the periodontium and the treatment protocol

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Clinical attachment loss. Timepoint: At the beginning of the study and 12 weeks after the start of vitamin D intake. Method of measurement: Williams periodontal probe.

Secondary Outcome Measures

Name	Time	Method
Probing depth. Timepoint: At the beginning of the study and 12 weeks after the start of vitamin D intake. Method of measurement: Williams periodontal probe.;Bleeding on probing. Timepoint: At the beginning of the study and 12 weeks after the start of vitamin D intake. Method of measurement: Williams periodontal probe.