Quadratus Lumborum (QL) Nerve Block for Patients Undergoing Primary Total Hip Arthroplasty (THA)
Overview
- Phase
- Early Phase 1
- Intervention
- Active Comparator
- Conditions
- Pain, Postoperative
- Sponsor
- University of California, Los Angeles
- Enrollment
- 80
- Locations
- 1
- Primary Endpoint
- Pain score
- Status
- Recruiting
- Last Updated
- 4 months ago
Overview
Brief Summary
The quadratus lumborum (QL) block is a fascial plane block that has been described to provide analgesia from T7-L3 dermatomes. The investigators aim to evaluate the efficacy of QL blocks in patients undergoing primary total hip arthroplasty (THA).
Detailed Description
Investigators will enroll subjects planned for primary THA and allocate them into receiving a QL block with either saline or ropivacaine. Primary outcome will be pain scores over the first 48 hours after surgery.
Investigators
Pamela Chia
HS Assistant Professor
University of California, Los Angeles
Eligibility Criteria
Inclusion Criteria
- •Adult subjects undergoing elective primary total hip arthroplasty
Exclusion Criteria
- •patients age \< 18,
- •documented allergy to local anesthetic
- •presence of peripheral neuropathy
- •patients with current long term opioid use defined as receiving an opioid on most days in a 90 day period
- •patients with a contraindication to spinal and regional anesthesia such as coagulopathy or infection at the site of the regional technique.
Arms & Interventions
Intervention Group
Quadratus lumborum nerve block with 0.25% ropivacaine
Intervention: Active Comparator
Control Group
Quadratus lumborum nerve block with saline
Intervention: Placebo Comparator
Outcomes
Primary Outcomes
Pain score
Time Frame: Up to 48 hrs post op
Pain scores will be assessed over 48hrs postop using the visual analog score
Secondary Outcomes
- Time to first ambulation(Up to 1 week post surgery)
- Ambulation distance(Up to 1 week post surgery)
- Patient satisfaction(Until day of discharge from the hospital, up to 1 week post surgery)
- Opioid usage(Up to 48 hrs post op)
- Time to first stand(Up to 1 week post surgery)
- Length of hospital stay(Until discharge from hospital, up to 1 week post surgery)