Quadratus Lumborum (QL) Nerve Block for Patients Undergoing Primary Total Hip Arthroplasty (THA)
试验速览
- 阶段
- 1 期
- 状态
- Enrolling By Invitation
- 入组人数
- 80
- 试验地点
- 2
- 主要终点
- Pain score
研究概览
简要总结
The quadratus lumborum (QL) block is a fascial plane block that has been described to provide analgesia from T7-L3 dermatomes. The investigators aim to evaluate the efficacy of QL blocks in patients undergoing primary total hip arthroplasty (THA).
详细描述
Investigators will enroll subjects planned for primary THA and allocate them into receiving a QL block with either saline or ropivacaine. Primary outcome will be pain scores over the first 48 hours after surgery.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Prevention
- 盲法
- Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Adult subjects undergoing elective primary total hip arthroplasty
排除标准
- •patients age < 18,
- •documented allergy to local anesthetic
- •presence of peripheral neuropathy
- •patients with current long term opioid use defined as receiving an opioid on most days in a 90 day period
- •patients with a contraindication to spinal and regional anesthesia such as coagulopathy or infection at the site of the regional technique.
研究组 & 干预措施
Intervention Group
Quadratus lumborum nerve block with 0.25% ropivacaine
干预措施: Active Comparator (Drug)
Control Group
Quadratus lumborum nerve block with saline
干预措施: Placebo Comparator (Drug)
结局指标
主要结局
Pain score
时间窗: Up to 48 hrs post op
Pain scores will be assessed over 48hrs postop using the visual analog score
次要结局
- Time to first ambulation(Up to 1 week post surgery)
- Ambulation distance(Up to 1 week post surgery)
- Patient satisfaction(Until day of discharge from the hospital, up to 1 week post surgery)
- Opioid usage(Up to 48 hrs post op)
- Time to first stand(Up to 1 week post surgery)
- Length of hospital stay(Until discharge from hospital, up to 1 week post surgery)
研究者
Pamela Chia
HS Assistant Professor
University of California, Los Angeles