A randomised, controlled trial of exit site application of MedihoneyTM Antibacterial Wound Gel for the prevention of catheter-associated infections in peritoneal dialysis patients, The HONEYPOT Study

Phase 3

Completed

• Conditions: Peritoneal dialysis; Chronic renal failure; Renal and Urogenital - Kidney disease; Alternative and Complementary Medicine - Other alternative and complementary medicine

• Registration Number: ACTRN12607000537459
• Lead Sponsor: Australasian Kidney Trials Network

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2007-10-19
• Study Completion: 2013-01-29
• Last Update Posted: 5 July 2021

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 371

Inclusion Criteria

Receiving peritoneal dialysis.
Able to give informed consent.

Exclusion Criteria

Patients with a history of psychological illness or condition which interferes with their ability to understand or comply with the requirements of the study. Recent (within 1 month) exit site infection, peritonitis, or tunnel infection. Known hypersensitivity to, or intolerance of, honey or mupirocin. On long term antibiotics. Nasal carriage of mupirocin resistant Staphylococcus aureus.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Time to first episode of exit site infection, tunnel infection or peritonitis (whichever comes first)[Time from study entry]

Secondary Outcome Measures

Name	Time	Method
Costs[Assessed throughout the study period];Time to first episode of peritonitis[Time from study entry];Time to first tunnel infection[Time from study entry];Time to first exit site infection[Time from study entry];Time to infection-associated catheter removal[Time from study entry];Catheter-associated infection rates[Assessed throughout the study period];Occurrence of mupirocin-resistant microbial isolates[Assessed throughout the study period];Incidence of adverse reactions[Assessed throughout the study period]