Risk Factors for Metachronous Advanced Colorectal Lesions After Endoscopic Resection of Serrated Lesions

Changhai Hospital0 个研究点目标入组 750 人开始时间: 2026年6月1日最近更新: 2026年7月1日

适应症

试验速览

阶段: 不适用
状态: 尚未招募
发起方: Changhai Hospital
入组人数: 750
主要终点: The occurrence of metachronous ACN

研究概览研究设计入排标准结局指标研究者记录与标识符相似试验

研究概览

简要总结

This study aims to explore the risk factors associated with the development of ACN and same-site ACN in patients with SP, thereby informing the optimization of clinical surveillance strategies

研究设计

研究类型: Observational
观察模型: Cohort
时间视角: Retrospective

入排标准

年龄范围: 18 Years 至 —（Adult, Older Adult）
性别: All
接受健康志愿者: 否

入选标准

•Adult patients aged > 18 years;At least one SP detected during the index colonoscopy and pathologically confirmed as TSA or SSL (according to the 2019 WHO classification criteria);Underwent complete polypectomy during the index colonoscopy;Received regular follow-up at Changhai Hospital, with an interval of ≥ 6 months between the index and follow-up colonoscopies;Complete clinical and pathological data.

排除标准

•Incomplete colonoscopy or failed cecal intubation;Inadequate bowel preparation, defined as a Boston Bowel Preparation Scale (BBPS) score < 6 or a score < 2 in any bowel segment;Withdrawal time < 6 minutes;Diagnosis of hereditary cancer syndromes, such as familial adenomatous polyposis (FAP) or Lynch syndrome;Concurrent inflammatory bowel disease (IBD) or indeterminate colitis;History of colorectal cancer or other malignancies;Incomplete clinical or pathological records.

结局指标

主要结局

The occurrence of metachronous ACN

时间窗: At least 6 months after index colonoscopy

次要结局

未报告次要终点

研究者

发起方

Changhai Hospital

申办方类型

Other

责任方

Sponsor

相似试验

已完成

不适用

Risk of Metachronous Advanced Colorectal Neoplastic Among Individuals With Varying Numbers of Non-Advanced Adenomas Detected During Screening ColonoscopyColorectal Adenoma

NCT07302139Fudan University2,955

尚未招募

不适用

Colorectal Adenoma CohortColorectal Neoplasms

NCT07523035Second Affiliated Hospital, School of Medicine, Zhejiang University1,280

招募中

不适用

The Long-term Effect of Artificial Intelligence-assisted Colonoscopy on Risk of Metachronous Advanced Colonic LesionColonic Polyps

NCT07467928The University of Hong Kong404

已完成

不适用

Exploring the Predictive Effect of Intestinal and Oral Microbiota on the Efficacy of Neoadjuvant Radiotherapy and Chemotherapy for Locally Advanced Rectal Cancer Based on Machine Learning

NCT07346729Nanfang Hospital, Southern Medical University60

尚未招募

不适用

Should Colorectal Cancer screening be done in India?Healthy asymptomatic adults (Absence of weight loss, persistent fever, anaemia, diarrhoea, rectal bleeding, constipation (within past 1 year), persistent abdominal pain).

CTRI/2024/03/063839Indian Council of Medical Research (ICMR)6,500