CTRI/2013/02/003360招募中4 期
Efficacy of intravenous â??L-ornithine L-aspartateâ?? in reversal of overt acute hepatic encephalopathy in patients with liver cirrhosis: a prospective, randomized, double-blind, placebo controlled trial - HEAL (Hepatic Encephalopathy and LOLA)
试验速览
- 阶段
- 4 期
- 状态
- 招募中
- 入组人数
- 164
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
入选标准
- •a. Hepatic cirrhosis based on clinical, biochemical, radiological and/or histological data.
- •b. Patients with overt acute grade 2, 3 and 4 HE, according to the West Haven criteria.
- •c. Age of patient >18 years
- •d. Patients with or without a precipitating factor for the HE.
排除标准
- •a.Patients who are terminally ill (End Stage Liver Disease, MELD more than 15)
- •b.Chronic HE, on Lactulose or antibiotics
- •c.Acute superposed liver injury (hepatitis) or acute on chronic liver failure
- •d.Severe septicemia with shock
- •e.Hepatocellular carcinoma
- •f. Wilsonâ??s disease as the etiological factor of liver disease
- •g. Advanced cardiac or pulmonary disease
- •h.Acute renal failure or end stage renal disease
- •i.Neuro-degenerative disease or major psychiatric illness
- •j.Patients on sedatives or antidepressants
- •k.Pregnancy or breastfeeding
研究者
相似试验
招募中
不适用
Plasmapheresis plus LOLA in liver failure of children.CTRI/2023/02/049867Institute of Liver and Biliary Sciences
Unknown
4 期
Therapeutic Efficacy of Oral L-Ornithine-L-Aspartate on Minimal EncephalopathyHepatic EncephalopathyNCT00896831Hospital de Clinicas de Porto Alegre96
Unknown
2 期
Therapeutic Efficacy of L-Ornithine L-Aspartate Infusion in Patients With Acute Liver FailureAcute Liver FailureNCT00470314All India Institute of Medical Sciences, New Delhi150
已完成
3 期
Efficacy of L-Ornithine-L-Aspartate in Cirrhotics With Hepatic EncephalopathyHepatic EncephalopathyNCT00433368Aga Khan University108
招募中
1 期
Efficacy of intravenous Atropine in prevention of post spinal hypotension and bradycardia in cesarean section.Spinal anesthesia in cesarean section.Single liveborn infant, delivered by cesareanZ38.01IRCT20120915010841N18Hamedan University of Medical Sciences88