Neonatal Infection Surveillance Database
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Neonatal Infection
- Sponsor
- St George's, University of London
- Enrollment
- 12000
- Locations
- 1
- Primary Endpoint
- Features of bacterial infections
- Status
- Recruiting
- Last Updated
- 3 years ago
Overview
Brief Summary
NeonIN is a is a neonatal infection surveillance database which will facilitate active surveillance for bacterial infections through a network of neonatal units, using standardised definitions, proformas and microbiological techniques. The centralised and secure web-based database will allow real-time entry of data and rapid and timely analysis of results.
Detailed Description
The neonIN surveillance network captures data on episodes of invasive neonatal infection on a web-based database (www.neonin.org.uk). Over 25 UK neonatal units currently contribute to this database in real-time. An episode of neonatal infection is defined as a positive culture collected from a normally sterile site such as the blood, cerebrospinal fluid (CSF) or urine (via catheter or suprapubic aspirate) for which clinicians prescribed at least five days of appropriate antibiotics. Clinical, demographic and microbiological data (including antimicrobial susceptibilities) are collected using a standardised online questionnaire, and denominator data regarding the total number of live-births and neonatal-admissions are collected for each neonatal unit.
Investigators
Eligibility Criteria
Inclusion Criteria
- •Infants on participating Neonatal Units who have an episode of infection with a positive culture
Exclusion Criteria
- Not provided
Outcomes
Primary Outcomes
Features of bacterial infections
Time Frame: 6 months
Collection of neonIN data on gestation, birth weight, age of onset, clinical presentation and prior antibiotic use of significant neonatal bacterial infections
Incidence of infection
Time Frame: 6 months
Collection of neonIN data on episodes of significant neonatal bacterial infections in NNUs recruiting to neonIN
Antibiotic susceptibility
Time Frame: 6 months
Collection of neonIN data on susceptibility profiles of significant neonatal bacterial infections