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临床试验/NCT05538299
NCT05538299招募中不适用

Silicosis Prevalence and Related Knowledge, Attitudes and Practices Among Mine Workers in Rural Rwanda

Samuel Hatfield1 个研究点 分布在 1 个国家目标入组 995 人开始时间: 2022年7月31日最近更新:
适应症

试验速览

阶段
不适用
状态
招募中
发起方
入组人数
995
试验地点
1
主要终点
Silicosis Prevalence

研究概览

简要总结

Silicosis is the most prevalent occupational lung disease in low- and middle-income countries (LMICs) with "tens of millions" estimated to suffer from the disease according to the World Health Organization (WHO). To date, there is little published data on silicosis in LMICs and the burden of silicosis in Rwanda has not been well-defined. Silicosis among local mine workers is a common reason for hospitalization and death at Rwinkwavu District Hospital, located in Rwanda's Kayonza District.

The objectives of this study are:

  1. To assess the prevalence of silicosis among workers in four mines located in the Kayonza District of Rwanda
  2. To adapt a validated screening tool testing in Dutch construction workers for Rwandan miners
  3. To implement an occupational health education program and assess the change of before and after intervention that target towards proper use of PPE and individual risk assessment in mine workers using knowledge-attitudes-practice tool

详细描述

Based on the clinical experience of the investigators and their network, silicosis morbidity and mortality have been consistently encountered among Rwandans with dust and mining exposure, however Rwanda currently lacks an existing body of data on current silicosis prevalence and a surveillance system for ongoing monitoring and interventions. According to the WHO, disease surveillance programs should include periodic identification and collection of health information, evaluation and interpretation of the information, and reporting and interventions for the purpose of prevention. The goal of surveillance is to monitor the trends in disease incidence over time across a particular domain, define the magnitude or relative magnitude of a problem and target and evaluate interventions. Here, the investigators propose a study of silicosis-related data from mine workers in Rwanda's Eastern Province through the development of a silicosis surveillance and health education program at Rwinkwavu District Hospital.

Methodology:

Study setting:

This study will be conducted in four sectors (Rwinkwavu, Murama, Ruramira, and Mwiri) of Kayonza district in eastern Rwanda. There are 9 [Migera, Gihinga, Nyarunazi, Gahengeli, Gashushyi, Rutonde, Raveri, Bugambira, Rukira] mining sites in Rwinkwavu, Murama, Ruramira and Mwiri, and all mining activities in these sites are supervised by Wolfram Mining and Processing LTD. All these sectors are located in the Rwinkwavu District Hospital catchment area.

Study design:

研究设计

研究类型
Observational
观察模型
Cohort
时间视角
Cross Sectional

入排标准

性别
All
接受健康志愿者

入选标准

  • Miners with greater than 1 year of potential exposure to respirable crystalline silica within the defined catchment area of the study

排除标准

  • non-mining (administrative, low risk of exposure) workers within the WOLFRAM (mining company) catchment area

结局指标

主要结局

Silicosis Prevalence

时间窗: 6 months

Estimate Silicosis prevalence in the Eastern Province of Rwanda

次要结局

  • Questionnaire Validation(1 year)
  • Knowledge, Action, Prevelence(1 year)

研究者

发起方
Samuel Hatfield
申办方类型
Other
责任方
Sponsor Investigator
主要研究者

Samuel Hatfield

Co-Investigator

Partners in Health

研究点 (1)

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