Risk Factors for Post Operative Nausea and Vomiting(PONV) in Patients Underwent Gynecological Operation Under General Anesthesia

Completed

• Conditions: Anesthesia, General; Elective Gynecological Operation; Chinese Female Patient; Adult

• Registration Number: NCT01020201
• Lead Sponsor: Huazhong University of Science and Technology

Brief Summary

Risk factors for postoperative nausea and vomiting(PONV) such as past history of PONV and/or motion sickness, non-smoking status, female gender, planned opiate use for post-operative analgesia were identified in white people. Whereas, risk factors for PONV in female patient with mongolian race were not clear. As a different life style and genetic background, new risk factors may associate with PONV in this population. The present study is a prospective cohort study to identify risk factors for PONV within 24 postoperative hours in chinese female patients underwent gynecology operative under general anesthesia.

Detailed Description

Not available

Study Timeline

• Study Start: 2009-02
• Primary Completion: 2009-05
• Study Completion: 2009-05
• Study First Submitted: 2009-11-24
• Study First Submitted QC: 2009-11-24
• Study First Posted: 2009-11-25
• Status Verified: 2012-07
• Last Update Submitted: 2012-07-30
• Last Update Posted: 2012-07-31

Recruitment & Eligibility

• Status: COMPLETED
• Sex: Female
• Target Recruitment: 774

Inclusion Criteria

• >18 years old
• Chinese female patient

Exclusion Criteria

• Unstable vital sign
• Patients under mechanical ventilation
• Patients under sedition (RASS=<-2)

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Incidence of postoperative nausea and vomiting	within 24 postoperative hours

Secondary Outcome Measures

Name	Time	Method
Incidence of postoperative shivering	within 24 postoperative hours
Postoperative pain score with Numerical Rating Scale (NRS-11)	within 24 postoperative hours
Time to full recovery of intestinal function	within 24 postoperative hours
Preoperative and postoperative fasting time	within 24 postoperative hours
Length of postoperative hospital stay and Length of hospital stay	before discharge
Total health care costs	before discharge
Postoperative delirium in recovery room	within PACU stay

Trial Locations

Locations (1)

Department of Anaesthesiology, Tongji Hospital of Tongji Medical College, Huazhong University of Science and Technology; 🇨🇳 Wuhan, Hubei, China