Разработка системы поддержки принятия клинических решений для тяжелых больных с политравмой

This study aimed to develop a Clinical Decision Support System for the management of severe polytrauma patients at the early inpatient care stage.

Scientific Hypothesis: It is assumed that the use of a clinical decision Support System at the stage of early inpatient care may reduce the mortality rate and adverse outcomes in severe patients with polytrauma.

Study setting The study is planned as a multicenter, non-interventional study, with participation from clinics providing inpatient trauma care for patients with polytrauma. The participating clinics will be selected based on their ability to provide access to a large and diverse population of patients with polytrauma. The research subgroup will be determined by clinics in compliance with the necessary ethical standards. The study will be conducted both retrospectively and prospectively, with data collection spanning a period of at least two years. Retrospective data will be collected from patients' medical records, including information on patient demographics, injury characteristics, diagnostic tests, and treatment modalities. Prospective data will be obtained through standardized patient interviews and clinical assessments, including patient-reported outcomes, clinical measures of physical and psychological functioning, and healthcare utilization. All participating clinics will be required to comply with the rules of medical ethics and deontology as well as local regulations governing access to personal data. In addition, researchers will be required to obtain informed consent from patients or their legal representatives before collecting any data for the study.

Obtained data:

Gender, Age, AIS code for every registered injury, NISS, Vitals on Admission (pulse rate, systolic and diastolic blood pressure, respiratory rate), Complete Blood Count on Admission (Red Blood Cells, Hematocrit, Hemoglobin, Platelets, White Blood Cells), biochemical analysis of blood on admission (total protein, total bilirubin, glucose, urea, creatinine), Blood Coagulation test (Activated Partial Thromboplastin Time, International Normalized Ratio, Fibrinogen), amount of total transfused blood and plasma packs, presence of complications (systemic inflammatory response syndrome, shock, severe hemorrhage [>25% of blood loss], acute traumatic coagulopathy, respiratory distress, pneumonia), length of stay in hospital, length of stay in the intensive care unit, and outcome at hospital discharge.