Clinical and demOgRaphic Features of Patients With Uncontrolled Severe Asthma in Russia (CORSAR)

Recruiting

• Conditions: Severe Asthma

• Registration Number: NCT06472310
• Lead Sponsor: AstraZeneca

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2024-5-22
• Last Update Posted: 2 September 2024

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 5000

Inclusion Criteria

Inclusion Criteria:<br><br> 1. Age = 18 years at the time of inclusion;<br><br> 2. Signed and dated written informed consent in accordance with ICH GCP and local law<br> prior to inclusion in the study;<br><br> 3. Patients with diagnosis of uncontrolled SA (Asthma Control Questionnaire-5 (ACQ-5)<br> score > 1,5) established no less than 52 weeks prior to inclusion; Severe asthma is<br> defined as asthma, that is controlled due to treatment with ICS in medium or high<br> doses plus LABA and/or ALP, and/or LAMA, and/or systemic corticosteroids (sCS),<br> and/or immunobiological therapy, while attempts to reduce the volume of therapy lead<br> to a loss of symptom control, or asthma remains uncontrolled despite this treatment.<br> Such therapy should be carried out at least 3 months before inclusion.<br><br> Uncontrolled asthma is defined as ACQ-5>1.5.<br><br> 4. Patients with the availability of at least 52 weeks of follow-up data (prior to<br> inclusion) in the medical records.<br><br>Exclusion Criteria:<br><br> 1. Patients receiving any biological therapy currently or within 52 weeks prior to<br> inclusion;<br><br> 2. Presence of chronic obstructive pulmonary disease (COPD) or idiopathic pulmonary<br> fibrosis (ILF) currently or in the anamnesis;<br><br> 3. The participation in any clinical study currently or within 52 weeks prior to<br> inclusion;<br><br> 4. An acute or chronic disease that, as deemed by Investigator, limits the ability of<br> patients to participate in this study or could influence the interpretation of the<br> results.

Exclusion Criteria

Not provided

Study & Design

• Study Type: Observational
• Study Design: Not specified