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Clinical Trials/NCT04753398
NCT04753398
Withdrawn
Not Applicable

One Heart to Care for, Your Heart to Take Care of.

Hasselt University1 site in 1 countryJanuary 2014
ConditionsHeart Failure

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Heart Failure
Sponsor
Hasselt University
Locations
1
Primary Endpoint
Mean medication doses
Status
Withdrawn
Last Updated
5 years ago

Overview

Brief Summary

This is an open randomized clinical trial with two study arms. One group, receiving usual care for heart failure, will be compared to another group, receiving usual care plus active telemonitoring interference.

When leaving the hospital, the usual care arm receives a document with a predefined medication scheme and advice for the general practitioner (like it is currently done in usual care). Besides the normal consultations at 2 and 5 weeks, no active interactions take place between the study nurse and the patient.

The telemonitoring interference in the other study arm consists of an automatic blood pressure device and medication dispenser that transmit data to a central platform. During the first 12 weeks, the nurse of the call center will give incentive for medication up titration on the basis of the available data. Before up titration can be done, the patient needs to take blood pressure measurements 3 times in the morning and 3 times in the evening and at least 6 measurements a week.

Registry
clinicaltrials.gov
Start Date
January 2014
End Date
December 2016
Last Updated
5 years ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Sponsor
Hasselt University
Responsible Party
Principal Investigator
Principal Investigator

Pieter Vandervoort

prof. dr.

Hasselt University

Eligibility Criteria

Inclusion Criteria

  • - Age ≥ 50
  • Patient has to be followed in Ziekenhuis Oost-Limburg or Jessa Ziekenhuis Hasselt
  • The patient has to be able to live independently or in a service flat
  • The diagnosis of heart failure or severe myocardial infarction has to be done after September 1, 2013 according to:
  • Left ventricular ejection fraction (LVEF) \<40%
  • eGFR\>30ml/min/kg
  • Treatment minimally with ACE-I and BB
  • The general practitioner had to give his approval for the installation of telemonitoring On the basis of an interview between the heart failure nurse and patient, one will decide if the patient is eligibil to join the study. The patient also needs to speak sufficient Dutch to be communicative about his/her medical condition.

Exclusion Criteria

  • Reversible form of heart failure
  • Heart failure due to severe aortic stenosis
  • eGFR less than 30ml/min/kg
  • Presence of a cardiac resynchronization therapy (CRT) device
  • Palliative status following the RIZIV guidelines or according to the assessment of the cardiologist (\<1 year)
  • Patients staying in a nursing or retirement home
  • Active treatment with either ACE-I/ARB or BB

Outcomes

Primary Outcomes

Mean medication doses

Time Frame: week 24

Define whether the mean medication doses of angiotensin-converting-enzyme inhibitor (ACE-I) and bètablockers (BB) in the group with telemonitoring is higher than in the group with usual care (without telemonitoring) after 6 months

Secondary Outcomes

  • All-cause mortality(Up to one year)
  • Medication titration(up to one year)
  • All cardio-related hospitalisations (number and time)(Up to one year)
  • All heart failure hospitalisations(Up to one year)
  • Number of (telephone) contacts for the encouragement of medication compliance(Up to one year)
  • Number of (telephone) contacts, registered by the heart failure nurse(Up to one year)
  • Satisfaction survey(month 12)
  • Number of medical practitioner-patient contacts(Up to one year)
  • Evolution of heart failure and comorbidities(up to one year)
  • Quality of life according to the HeartQoL questionnaire(day 1, month 12)

Study Sites (1)

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