Mechanisms of hepatic fat reduction through nutritional strategies in patients with indication for bariatric surgery
Not Applicable
Recruiting
- Conditions
- E66.82
- Registration Number
- DRKS00009509
- Lead Sponsor
- Deutsches Institut für Ernährungsforschung Potsdam- Rehbrücke, Abteilung Klinische Ernährung
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 60
Inclusion Criteria
Obese patients with BMI > 40 kg/m² or BMI > 35 kg/m² and obesity related co-morbidities (type 2 diabetes, hypertension, dyslipidemia, obstructive sleep apnoe syndrome);
failed 6 months multimodal standardized conservative obesity therapy;
indication for bariatric procedure;
written informed consent
Exclusion Criteria
1. Taking medications that lead to insulin resistance (cortisol, growth hormone, rheumatism)
2. Chemotherapy within 8 weeks before surgery
3. An advanced liver disease (cirrhosis)
4. Patients who have already received an organ transplant
5. Patients with severe infectious disease
6. Any factors that limit the ability of the patient to cooperate during study ( mental function or drug abuse)
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Change of liver fat content after three weeks of dietary intervention using MRT scan (t0: before diet; t1: after three weeks of diet)
- Secondary Outcome Measures
Name Time Method