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Clinical Trials/NCT02302911
NCT02302911
Unknown
N/A

Swiss Early Intervention Project in Autism: An Evaluation of Early Intervention Outcome

University of Zurich3 sites in 1 country90 target enrollmentJanuary 2013

Overview

Phase
N/A
Intervention
Not specified
Conditions
Autism Spectrum Disorder
Sponsor
University of Zurich
Enrollment
90
Locations
3
Primary Endpoint
Autism Diagnostic Observation Schedule-2 (ADOS-2)
Last Updated
8 years ago

Overview

Brief Summary

This study aims to investigate the effectiveness of early (before the age of 5 years) and intensive intervention for children with Autism Spectrum Disorders.

Detailed Description

This study aims to investigate the effectiveness of early (before the age of 5 years) and intensive intervention for children with Autism Spectrum Disorders. The type of intervention proposed in Switzerland differs greatly depending on where people live. Several international studies show positive outcomes in children with Autism after receiving early behavioural intervention. However, Disability Insurance (DI) in Switzerland does not fully cover these scientifically proven interventions. Since January 2014 they cover 45 000 CHF per child for only two years of early treatment across five centres chosen by the Federal Social Insurance Office. The remaining costs are covered by the parents, foundations or by the cantons. In addition, families benefit from this early intervention only if their child is enrolled in one of the five selected centres. There are currently various types of support for children with Autism in Switzerland before age five, early intensive behavioural interventions, eclectic early intervention and less intensive interventions with a treatment that is not specific to Autism (about 3 hrs./week), which includes occupational therapy, speech therapy and early curative education. Some children do not receive any treatment. This research aims to evaluate the efficacy of these interventions (early intensive behavioural/ eclectic/treatment as usual) as has been done previously in international studies. The study also aims to include centres other than those selected by the Swiss Federal Social Insurance Office.

Registry
clinicaltrials.gov
Start Date
January 2013
End Date
December 2018
Last Updated
8 years ago
Study Type
Observational
Sex
All

Investigators

Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • Not provided

Exclusion Criteria

  • Experimental Group:
  • receipt of a second intervention that either interferes with the intensive Intervention or is also intensive (more than 10 hours a week)
  • Comparison Group:
  • receipt of any Intervention that is more than 10 hours a week

Outcomes

Primary Outcomes

Autism Diagnostic Observation Schedule-2 (ADOS-2)

Time Frame: Annually up to 3 years

Measures autism symptom severity

Secondary Outcomes

  • Vineland Adaptive Behavior Scales II (VABS)(Annually up to 3 years)
  • Positive Gain Scale(Annually up to 3 years)
  • General Positive Affect Scale(Annually up to 3 years)
  • Questionnaire on Resources and Stress(Annually up to 3 years)
  • Hospital anxiety and Depression scale(Annually up to 3 years)
  • Strengths and Difficulties Questionnaire(Annually up to 3 years)
  • Snijders-Oomen nicht-verbaler Intelligenztest 2 1/2 - 7 (SON-R)(Annually up to 3 years)
  • Wechsler Preschool and Primary Scale of Intelligence-III (WPPSI-III)(Annually if child is testable up to 3 years)

Study Sites (3)

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