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Randomized controlled trial to compare oral iron to parenteral iron therapy for correction of iron deficiency in chronic kidney disease.

Not Applicable
Conditions
Health Condition 1: D508- Other iron deficiency anemias
Registration Number
CTRI/2020/04/024881
Lead Sponsor
Dr Manu Dogra
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
ot Yet Recruiting
Sex
Not specified
Target Recruitment
0
Inclusion Criteria

1. Iron deficiency defined as TSAT < 30 % and serum ferritin < 500mg/dL

2. Clinically stable course for last 3 months

Exclusion Criteria

1.Blood hemoglobin < 9 g/dl

2.Current use or use within last 3 months of oral or intravenous iron preparations

3.Known / suspected diagnosis of autoimmune disease

4.Past or present diagnosis of malignancy

5.Known diagnosis of chronic liver disease

6.History of any bleeding diathesis

7.History of gastro-intestinal surgery

8.Present or past diagnosis of peptic ulcer disease, gastro-intestinal bleeding or any form of gastro-intestinal disease predisposing to malabsorption

9.Currently taking gastric acid inhibitors (H2 receptor blockers, proton pump inhibitors)

10.History of allergic reactions to any form of oral or intravenous iron preparations

11.History of prior non-compliance with oral iron therapy due to gastro-intestinal side effects

12.Current use or use within last 6 months of immunosuppressive drug therapy

13.Pregnancy or lactation, in case of females

14.Life expectancy < 1 year

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Secondary Outcome Measures
NameTimeMethod
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