Consciousness processes in patients with disorders of consciousness/vegetative state

Recruiting

• Conditions: minimally conscious state; G93.80

• Registration Number: DRKS00003260
• Lead Sponsor: niversität TübingenInstitut für medizinische Psychologie und Verhaltensneurobiologie

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2011-11-22
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 80

Inclusion Criteria

vegetative state, minimally conscious state

Exclusion Criteria

missing acoustically evoked potentials (AEP), epileptic potentials in electroencephalography (EEG), sedating medication, magnetic resonance imaging (MRI) contraindications

Study & Design

• Study Type: observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
measuring of the BOLD signal with fMRI (1,5 T Siemens TIM Symphony Scanner) in 5 different paradigms: <br>- mental imagery<br>- language comprehension<br>- trace conditioning<br>- emotional empathy<br>- pain perception<br>The main goal of this project is to develop a method to find indications for cognitive and emotional conscious perception, including pain perception, in patient with disorders of consciousness.<br>

Secondary Outcome Measures

Name	Time	Method
Exploring neuronal basics of conscious perception:<br>- conscious perception needs activation in secondary associative brain areas, needs integration of different areas (e.g. thalamus, precuneus) and needs synchronisation of different brain regions.<br><br>