Comparison of the effectiveness of two different respiratory exercise training methods in prolonged ventilated patients

Not Applicable

Completed

• Conditions: Respiratory muscle dysfunction in prolonged ventilated patients; Respiratory

• Registration Number: ISRCTN15425727
• Lead Sponsor: Connolly Hospital Blanchardstown

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2020-07-05
• Study Completion: 2021-12-31
• Last Update Posted: 31 October 2022

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 30

Inclusion Criteria

1. Adult patients 18 years or above admitted to general critical care unit and required mechanical ventilation support for more than five days
2. Patients who can respond to the verbal command and can tolerate breathing exercises such as deep breath in and out”
3. Richmond Agitation-Sedation Scale score 0

Exclusion Criteria

1. Medically unstable during critical care admission and prolonged ventilation period before training
2. Use of more than minimal continuous infusion inotropic agents
3. Contraindication to disconnect the patient from the mechanical ventilator for RMT treatment or IMT treatment
4. Acute coronary artery disease
5. Thoracic contraindications

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Maximum Inspiratory Pressure (MIP) measured using CE marked Micro RPM (Respiratory Pressure Monitor) at pre-(baseline) and post-intervention (2 weeks). 3 trials are taken and the highest value will be used.

Secondary Outcome Measures

Name	Time	Method
<br> Measures will be performed pre-(baseline) and post-intervention (2 weeks):<br> 1. Maximum Expiratory Pressure (MEP) will be measured using a pressure manometer - 3 trials are taken and the highest value will be used<br> 2. Cough strength will be measured using a semi-quantitative cough strength score<br> 3. Fatigue resistance index will be measured using the ratio of MIP, post-training with Inspiratory Muscle Trainer/MIP pre-training.<br> 4. Rectus abdominis muscle thickness assessment will be measured using a diagnostic ultrasound machine<br> 5. Hand dynamometry will be measure peripheral muscle function – 3 trials are taken on the participants dominant hand and the highest value will be used<br>