Stem Cell Therapy in Incurable Neurological Disorders
Phase 1
Withdrawn
- Conditions
- Neurological; Disorder, Nervous System
- Interventions
- Biological: Stem Cell
- Registration Number
- NCT02245776
- Lead Sponsor
- Neurogen Brain and Spine Institute
- Brief Summary
The purpose of the study was to analyze the benefit of autologous mononuclear cell therapy in incurable neurological disorders.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- WITHDRAWN
- Sex
- All
- Target Recruitment
- Not specified
Inclusion Criteria
- diagnosed cases of incurable neurological disorders
- age above 6 months
Exclusion Criteria
- presence of acute infections such as Human immunodeficiency virus/Hepatitis B Virus/Hepatitis C Virus
- malignancies
- bleeding tendencies
- pneumonia
- renal failure
- severe liver dysfunction
- severe anemia [Hemoglobin < 8]
- any bone marrow disorder
- space occupying lesion in brain
- other acute medical conditions such as respiratory infection and pyrexia
- pregnancy
- lactation
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- SINGLE_GROUP
- Arm && Interventions
Group Intervention Description Stem Cell Stem Cell Bone marrow mononuclear cell transplantation
- Primary Outcome Measures
Name Time Method Change in various clinical symptoms of neurological disorders 1 year Change in various symptoms such as muscle strength, limb strength, ambulation, neck holding, bladder bowel management, spasticity, sensation, speech, etc depending on the disorder will be recorded at 1 year follow up. Percentage analysis of each symptom will be carried out to study the benefits of stem cell therapy on them.
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
Neurogen brain and spine institute
🇮🇳Navi Mumbai, Maharashtra, India