NCT02245776撤回1 期
Autologous Bone Marrow Mononuclear Cell Therapy for Incurable Neurological Disorders
适应症
干预措施
试验速览
- 阶段
- 1 期
- 状态
- 撤回
- 试验地点
- 2
- 主要终点
- Change in various clinical symptoms of neurological disorders
研究概览
简要总结
The purpose of the study was to analyze the benefit of autologous mononuclear cell therapy in incurable neurological disorders.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 6 Months 至 80 Years（Child, Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •diagnosed cases of incurable neurological disorders
- •age above 6 months
排除标准
- •presence of acute infections such as Human immunodeficiency virus/Hepatitis B Virus/Hepatitis C Virus
- •malignancies
- •bleeding tendencies
- •pneumonia
- •renal failure
- •severe liver dysfunction
- •severe anemia [Hemoglobin < 8]
- •any bone marrow disorder
- •space occupying lesion in brain
- •other acute medical conditions such as respiratory infection and pyrexia
- •pregnancy
- •lactation
研究组 & 干预措施
Stem Cell
Experimental
Bone marrow mononuclear cell transplantation
干预措施: Stem Cell (Biological)
结局指标
主要结局
Change in various clinical symptoms of neurological disorders
时间窗: 1 year
Change in various symptoms such as muscle strength, limb strength, ambulation, neck holding, bladder bowel management, spasticity, sensation, speech, etc depending on the disorder will be recorded at 1 year follow up. Percentage analysis of each symptom will be carried out to study the benefits of stem cell therapy on them.
次要结局
未报告次要终点
研究者
研究点 (2)
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