A retrospective, case-control study to compare and evaluate the fatigability with video-oculography in myasthenia gravis patients
- Conditions
- Diseases of the nervous system
- Registration Number
- KCT0007430
- Lead Sponsor
- Jeonbuk National University Hospital
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot yet recruiting
- Sex
- All
- Target Recruitment
- 70
? Criteria for selecting patients with myasthenia gravis
All patients who meet the following criteria:
• Adults between 19 and 70 years of age
• In case myasthenia gravis is diagnosed through one of the following tests, while there are fluctuations that improve in the morning and worsen in the afternoon, or there is muscle weakness such as muscle weakness, diplopia, ptosis, dysarthria, etc.
o Serum acetylcholine receptor antibody positive
o Repetitive nerve stimulation test to check muscle fatigue
o Confirmation of symptom improvement through drug reaction in Tensilon test
o Symptom improvement confirmed by ice pack test
• Patients who underwent an eye movement test
? Control group selection criteria
• Adults between 19 and 70 years of age
• Patients with no symptoms of myasthenia gravis and no history of diagnosis
• Patients who underwent an eye movement test
1) Patients with abnormal findings in neurological examination
2) Patients with structural abnormalities of the brain
3) Patients who did not perform eye movement test
4) Patients who do not meet the selection criteria
Study & Design
- Study Type
- Observational Study
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Video-oculography(Saccade, Smooth pursuit)
- Secondary Outcome Measures
Name Time Method Characteristics of clinical symptoms in patients with myasthenia gravis