Prevalence of Psoriatic Arthritis in Adults With Psoriasis: An Estimate From Dermatology Practice
Trial Snapshot
- Phase
- Phase 4
- Status
- Completed
- Sponsor
- Pfizer
- Enrollment
- 1,013
- Locations
- 45
- Primary Endpoint
- Percentage of Participants With Psoriatic Arthritis (PsA) Based on Physical Examination, Medical History and Laboratory Results
Study Overview
Brief Summary
This is a phase 4, multicenter, randomized, non-therapeutic interventional trial in subjects with psoriasis looking for the prevalence of psoriatic arthritis. Subjects will be seen and evaluated by a dermatologist at visit 1 and by a rheumatologist at visit 2. A subset of subjects will then go on to visit 3 for imaging procedures (x-ray, MRI, and ultrasound).
Study Design
- Study Type
- Interventional
- Allocation
- Randomized
- Intervention Model
- Parallel
- Primary Purpose
- Diagnostic
- Masking
- None
Eligibility Criteria
- Ages
- 18 Years to — (Adult, Older Adult)
- Sex
- All
- Accepts Healthy Volunteers
- No
Inclusion Criteria
- •Subject is >18 years of age at the time of consent.
- •Subject has a confirmed diagnosis of plaque psoriasis by clinical judgment.
- •Subject is able to read and complete questionnaires.
- •Subjects planning to undergo radiographic evaluation, should not have any contraindications to MRI.
Exclusion Criteria
- Not provided
Arms & Interventions
psoriatic arthritis (PsA) questionnaire
Intervention: lab draws and imaging (Procedure)
Outcomes
Primary Outcomes
Percentage of Participants With Psoriatic Arthritis (PsA) Based on Physical Examination, Medical History and Laboratory Results
Time Frame: Week 0 through Week 8
PsA: inflammatory arthritis associated with psoriasis that can have an indolent and progressive course. Percentage of participants with PsA was calculated by dividing the number of participants who were classified as positive by the rheumatologist and the total number of participants evaluated using medical history, physical examination and laboratory results as the basis for the diagnosis.
Secondary Outcomes
- Percentage of Participants With Undiagnosed Psoriatic Arthritis (PsA)(Week 0 through Week 8)
- Percentage of Participants With Psoriatic Arthritis (PsA) Based on Physical Examination and Medical History(Week 0 through Week 8)