Clinical Diagnosis of Acute Appendicitis with Normal WBCS Count with Role of Inflammatory Markers and Radiology

Active, not recruiting

• Conditions: Acute Appendicitis

• Registration Number: NCT06834958
• Lead Sponsor: Assiut University

Brief Summary

The aim of this study is to describe the proportion of pa-tients with normal preoperative inflammatorymarkers among patients with histopathologically proven acute appendicitis

Detailed Description

2.4.1- Type of the study: prospective clinical trial study 2.4. 2- Study Setting: Assuit university hospital 2.4. 3- Study subjects:

1. Inclusion criteria:

patients complain of Rt iliac pain with Us positive for acute appendicitis with WBCS normal .

2. Exclusion criteria:

malignant mass cancer appendix mesenteric adentis cecal diverticulum salpingitis c. Sample Size Calculation: 50 cases 2.4.4 -Study tools (in detail, e.g., lab methods, instruments, steps, chemicals, ...): Lab WBCS count CRP level Neutrophil differential count Clinical correlation US findings and MSCT if needed

Study Timeline

• Study Start: 2025-01-01
• Study First Submitted: 2025-01-31
• Status Verified: 2025-02
• Study First Submitted QC: 2025-02-14
• Last Update Submitted: 2025-02-14
• Study First Posted: 2025-02-19
• Last Update Posted: 2025-02-19
• Primary Completion: 2027-10-01
• Study Completion: 2028-10

Recruitment & Eligibility

• Status: ACTIVE_NOT_RECRUITING
• Sex: All
• Target Recruitment: 50

Inclusion Criteria

Not provided

Exclusion Criteria

• complicated AA (perforation, peri appendicular abscess or suspicion of a tumor.

  2_inflammatory bowel diseases 3_inability to co-operate and give informed consent 4_diffuse peritonitis 5_Patients with serious comorbid conditions DM & renal insufficiency, serum creatinine > 150 μmol/l 6_Pregnant & lactating patient 7_Patients with advanced malignancies & pt on immunosuppressive drugs

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Surgery done if needed	Days of hospital reservation	Patient with acute appendicitis and normal WBCS count will be under observation for while but people with evidence on imaging and high inflammatory markers will go under surgery

Trial Locations

Locations (1)

Assuit university; 🇪🇬 Assuit, Egypt