MRI Analysis and Degenerative Spine
Recruiting
- Conditions
- Spine Disease
- Interventions
- Diagnostic Test: MRI advanced techniques
- Registration Number
- NCT06163300
- Lead Sponsor
- Universidade Nova de Lisboa
- Brief Summary
Analysis of MRI advanced techniques in degenerative spinal disease.
The main questions it aims to answer are:
* Can we assess microstructural integrity of compressed nerve roots in degenerative spinal disease
* What are the image biomarkers affected by disease
* How they evolve with disease progression and treatment
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- RECRUITING
- Sex
- All
- Target Recruitment
- 200
Inclusion Criteria
- Age between 50 and 85 years
- Diagnosis of spinal disease by clinical and imagiological criteria
- More than 3 months duration of disease
- Ability to give consent
- Fluent portuguese speaker
Exclusion Criteria
- Previous spine surgery
- Spinal instability
- Neurological disease that might interfere with walking
- Known orthopedic conditions that causes significant gait impairment
- Dementia or development disorder with cognitive impairment
- Inability to give consent
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Arm && Interventions
Group Intervention Description Disease MRI advanced techniques Patients affected by disease Control MRI advanced techniques Healthy volunteers
- Primary Outcome Measures
Name Time Method Lumbar Pain Intensity 18 months Measured using the Numeric Pain Rating Scale (range: 0 - 10 )
ODI - Oswestry Disability Index 18 months Measured using the ODI scale (range 0 - 50)
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
Hospital da Luz Setúbal
🇵🇹Setúbal, Portugal