A pilot investigation of the effects of repetitive transcranial magnetic stimulation (rTMS) in bulimic disorders: a two-armed double-blind randomised sham (placebo)-controlled trial

King's College London (UK)0 个研究点目标入组 40 人开始时间: 2009年11月4日最近更新: 2015年1月13日

适应症

试验速览

暂无简介。

•1. Outpatients
•2. Male and female
•3. Aged 18 to 60 years
•4. Body mass index (BMI) higher than 17.5 kg/m^2
•5. Diagnostic and Statistical Manual of Mental Disorders, 4th Edition (DSM-IV) diagnosis of bulimia nervosa, binge eating disorder or eating disorder not otherwise specified (EDNOS) with a minimum of six binge episodes in the last 28 days (as assessed by the Eating Disorder Examination - Questionnaire [EDE-Q])

•1. Having a history of head or eye injury
•2. Having a history of a neurological disease including previous seizures of any kind
•3. Having metallic implants in the head
•4. Being on a dose of any psychotropic medication that has not been stable for at least 14 days prior to participation in the study
•5. Being pregnant
•6. Smoking more than 10 cigarettes/day
•7. Having any substance dependence
•8. Participants who vomit on a regular basis (i.e. greater than 7 x a week), will be required to have a blood test to exclude those with electrolytes below the normal range
•9. Participants will not have any other major psychiatric disorder needing treatment in its own right
•10. Contraindications to rTMS as assessed with the Adult Safety Screen Questionnaire for rTMS
•11. Being primarily left-handed

发起方

King's College London (UK)