Effect of Atorvastatin and CoQ10 on stroke
- Conditions
- ischemic stroke.Cerebral infarction
- Registration Number
- IRCT2017041731773N1
- Lead Sponsor
- Vice chancellor for research, Shahid Beheshti University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 60
(patients with ischemic stroke involving the middle cerebral artery, confirmed by computed tomography scanning and clinical symptoms; range of age 50-70 years; not to receive statins continuously before entering the study; not to receive antioxidants (such as vitamin C and E) constantly; not to receive anti-inflammatory drugs (steroids, nonsteroidal anti-inflammatory) constantly; not affected by AIDS and neurodegenerative diseases (e.g. Alzheimer's, Parkinson's, amyotrophic lateral sclerosis, multiple sclerosis); no loss of consciousness level due to any reason except stroke (such as shock, alcohol consumption or intoxication); non-pregnancy; non-epilepsy; patient`s consent).Exclusion criteria: (patient's death during the study; lack of patient`s availability to follow-up; no tendency to attend in next follow-up).
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Degree of disability. Timepoint: Admission- After 30 day. Method of measurement: Modified Rankin Scale (MRS).;Glial fibrillary acidic protein(GFAP). Timepoint: admission- 72 houre-after 30 day. Method of measurement: eliza kit.;Cognitive performance. Timepoint: admission- 72 houre-after 30 day. Method of measurement: Mini-Mental State Examination(MMSE).;Motor function and verbal. Timepoint: admission- 72 houre-after 30 day. Method of measurement: National Institutes of Health Stroke Scale(NIHSS).
- Secondary Outcome Measures
Name Time Method