Acute peritoneal dialysis versus Intermittent hemodialysis in Acute Kidney Injury Patients

Phase 3

Recruiting

• Conditions: Acute Kidney Injury; Acute kidney injury

• Registration Number: TCTR20180914002
• Lead Sponsor: Division of Nephrology, Chulalongkorn University

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2018-09-14
• Study Completion: 2019-09-14
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 140

Inclusion Criteria

- Adult patients (at least 18 years old)
- AKI by KDIGO staging of 2
- Conventional indications for dialysis (refractory hyperkalemia, refractory acidosis, uremic symptoms, refractory fluid overload)

Exclusion Criteria

- CKD (Baseline GFR < 60 mL/min/1.73m2)
- Renal replacement therapy within 1 month
- Renal transplant
- Pregnancy
- Contraindicated for peritoneal dialysis catheter insertion (previous abdominal surgery, BMI >= 30 kg/m2)
- Contraindicated for dialysis catheter insertion (vascular thrombosis)
- Moribund state (Expected death within 24 hours)
- Terminally ill diseases (e.g. end-stage cancer)
- Serum K >= 7 mEq/L
- pH <= 7.0

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
28-day mortality 28 days Percentage,28-day mortality 28 days Percentage

Secondary Outcome Measures

Name	Time	Method
Dialysis dependence 28 days Percentage,Dialysis adequacy 3 days Kt/V,Renal recovery 28 days Percentage,Adverse events 28 days Percentage