IRCT20240501061618N1
Recruiting
Phase 2
Investigating the efficacy and safety of Curcumin on the prevention of non-alcoholic fatty liver disease (NAFLD) in patients with non-metastatic breast cancer receiving tamoxifen
Overview
- Phase
- Phase 2
- Intervention
- Not specified
- Conditions
- Fatty liver caused by tamoxifen in patients with non-metastatic breast cancer.
- Sponsor
- Esfahan University of Medical Sciences
- Enrollment
- 44
- Status
- Recruiting
- Last Updated
- last year
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •Women with non\-metastatic breast cancer whose pathology is positive in terms of hormone receptors and are treated with tamoxifen.
- •Normal liver enzymes
- •Not having viral hepatitis
- •Not having a history of alcohol consumption
- •Not using drugs with hepatotoxicity such as methotrexate, amiodarone, valproic acid, anabolic steroids, as well as the use of anticoagulant and antiplatelet drugs.
- •Insensitivity to curcumin drug
- •No history of chemotherapy
Exclusion Criteria
- •The patient's unwillingness to continue the study
- •Having liver diseases during the study
- •The use of drugs with hepatotoxicity such as methotrexate, amiodarone, valproic acid, anabolic steroids, as well as the use of anticoagulant and antiplatelet drugs after the start of the study.
- •Suffering from any related disease and distorting the results during the study
- •Allergic to curcumin drug
- •Development of Metastasis during the study
Outcomes
Primary Outcomes
Not specified
Similar Trials
Not yet recruiting
Phase 1
The evaluation the effect of nanocurcommin in people living with HIVIRCT20210216050373N4Tehran University of Medical Sciences100
Completed
Phase 3
Curcumin With and Without Strengthening Exercises in Rheumatoid ArthritisIRCT20220401054388N1Ali –Ul- Murtaza Department of Rehabilitation Science, MIMAS100
Not yet recruiting
Phase 2
The effect of curcumin (a substance extracted from turmeric) on the immune system and clinical signs in patients with rheumatoid arthritisIRCT20220309054225N1Yazd University of Medical Sciences30
Recruiting
Phase 1
Evaluation of the effectiveness of Curcumin in the improving patients with autoimmune hepatitisIRCT20221112056476N1Zahedan University of Medical Sciences68
Completed
Phase 3
Evaluation of the effectiveness of curcumin in the prevention of contrast induced nephropathy in following coronary AngiographyContrast induced nephropathy in following coronary angiography.Nephrotic syndromeIRCT20190911044744N4Yazd University of Medical Sciences60