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Clinical Trials/NCT07556380
NCT07556380
Not yet recruiting
Not Applicable

SESAME: Sun Exposure and Activities After Skin Cancer: Optimization of mHealth Interventions

Northwestern University2 sites in 1 country150 target enrollmentStarted: April 1, 2026Last updated:

Overview

Phase
Not Applicable
Status
Not yet recruiting
Enrollment
150
Locations
2
Primary Endpoint
Feasibility: Retention Rates

Overview

Brief Summary

The purpose of this study is to evaluate 5 different smartphone administered sun protection interventions that aim to reduce unprotected sun exposure in melanoma survivors. Participants are asked to wear an ultraviolet (UV) device and an activity monitor (Actigraph) to measure their daily UV exposure and track their physical activity for three separate assessment weeks and complete daily surveys. After the first assessment week, eligible participants are assigned up to 5 different sun protection interventions that are administered through a smartphone application for 8 weeks. Following 8-week use of the sun protection interventions, participants complete another assessment week. At the end of the assessment week, participants provide feedback on the design and usability of the UV device, smartphone application and each of the sun protection interventions that they experienced. One year later, participants are contacted again to complete a final assessment week.

Study Design

Study Type
Interventional
Allocation
Randomized
Intervention Model
Factorial
Primary Purpose
Prevention
Masking
None

Eligibility Criteria

Ages
18 Years to — (Adult, Older Adult)
Sex
All
Accepts Healthy Volunteers
No

Inclusion Criteria

  • Is able to speak, read and write in English
  • Had previous melanoma diagnosis with no melanoma treatment in the last three months
  • Has no current Melanomas or untreated skin cancer
  • Reports spending at least 15 minutes outside per day during Spring/ Summer on both weekdays and weekends
  • Owns a smartphone with access to both Bluetooth and WIFI
  • Is willing to use the UV device and Actigraph during waking hours
  • Is willing to download and use a study app
  • Is willing to actively participate in the study for up to 1 year

Exclusion Criteria

  • Has a medical condition preventing moderate-to-vigorous physical activity (MVPA) or a doctor recommendation to avoid MVPA
  • Is currently enrolled in another study on MVPA

Arms & Interventions

Experimental Condition 2

Experimental

Research participant receives the Core Components + UV Real-Time Alerts + Track Your Sun Protection + Current Conditions + Health Coaching

Intervention: Track Your Sun Protection (Behavioral)

Experimental Condition 1

Experimental

Research participant receives the Core Components + UV Real-Time Alerts + Track Your Sun Protection + Current Conditions + Health Coaching + Action Planning

Intervention: UV Real-Time Alerts (Behavioral)

Experimental Condition 1

Experimental

Research participant receives the Core Components + UV Real-Time Alerts + Track Your Sun Protection + Current Conditions + Health Coaching + Action Planning

Intervention: Track Your Sun Protection (Behavioral)

Experimental Condition 1

Experimental

Research participant receives the Core Components + UV Real-Time Alerts + Track Your Sun Protection + Current Conditions + Health Coaching + Action Planning

Intervention: Current Conditions (Behavioral)

Experimental Condition 1

Experimental

Research participant receives the Core Components + UV Real-Time Alerts + Track Your Sun Protection + Current Conditions + Health Coaching + Action Planning

Intervention: Health Coaching (Behavioral)

Experimental Condition 1

Experimental

Research participant receives the Core Components + UV Real-Time Alerts + Track Your Sun Protection + Current Conditions + Health Coaching + Action Planning

Intervention: Action Planning (Behavioral)

Experimental Condition 1

Experimental

Research participant receives the Core Components + UV Real-Time Alerts + Track Your Sun Protection + Current Conditions + Health Coaching + Action Planning

Intervention: Core Components (Behavioral)

Experimental Condition 2

Experimental

Research participant receives the Core Components + UV Real-Time Alerts + Track Your Sun Protection + Current Conditions + Health Coaching

Intervention: UV Real-Time Alerts (Behavioral)

Experimental Condition 2

Experimental

Research participant receives the Core Components + UV Real-Time Alerts + Track Your Sun Protection + Current Conditions + Health Coaching

Intervention: Current Conditions (Behavioral)

Experimental Condition 2

Experimental

Research participant receives the Core Components + UV Real-Time Alerts + Track Your Sun Protection + Current Conditions + Health Coaching

Intervention: Health Coaching (Behavioral)

Experimental Condition 2

Experimental

Research participant receives the Core Components + UV Real-Time Alerts + Track Your Sun Protection + Current Conditions + Health Coaching

Intervention: Core Components (Behavioral)

Experimental Condition 3

Experimental

Research participant receives the Core Components + UV Real-Time Alerts + Track Your Sun Protection + Current Conditions + Action Planning

Intervention: Current Conditions (Behavioral)

Experimental Condition 3

Experimental

Research participant receives the Core Components + UV Real-Time Alerts + Track Your Sun Protection + Current Conditions + Action Planning

Intervention: UV Real-Time Alerts (Behavioral)

Experimental Condition 3

Experimental

Research participant receives the Core Components + UV Real-Time Alerts + Track Your Sun Protection + Current Conditions + Action Planning

Intervention: Track Your Sun Protection (Behavioral)

Experimental Condition 3

Experimental

Research participant receives the Core Components + UV Real-Time Alerts + Track Your Sun Protection + Current Conditions + Action Planning

Intervention: Action Planning (Behavioral)

Experimental Condition 3

Experimental

Research participant receives the Core Components + UV Real-Time Alerts + Track Your Sun Protection + Current Conditions + Action Planning

Intervention: Core Components (Behavioral)

Experimental Condition 4

Experimental

Research participant receives the Core Components + UV Real-Time Alerts + Track Your Sun Protection + Current Conditions

Intervention: UV Real-Time Alerts (Behavioral)

Experimental Condition 4

Experimental

Research participant receives the Core Components + UV Real-Time Alerts + Track Your Sun Protection + Current Conditions

Intervention: Track Your Sun Protection (Behavioral)

Experimental Condition 4

Experimental

Research participant receives the Core Components + UV Real-Time Alerts + Track Your Sun Protection + Current Conditions

Intervention: Current Conditions (Behavioral)

Experimental Condition 4

Experimental

Research participant receives the Core Components + UV Real-Time Alerts + Track Your Sun Protection + Current Conditions

Intervention: Core Components (Behavioral)

Experimental Condition 5

Experimental

Research participant receives the Core Components + UV Real-Time Alerts + Track Your Sun Protection + Health Coaching + Action Planning

Intervention: UV Real-Time Alerts (Behavioral)

Experimental Condition 5

Experimental

Research participant receives the Core Components + UV Real-Time Alerts + Track Your Sun Protection + Health Coaching + Action Planning

Intervention: Track Your Sun Protection (Behavioral)

Experimental Condition 5

Experimental

Research participant receives the Core Components + UV Real-Time Alerts + Track Your Sun Protection + Health Coaching + Action Planning

Intervention: Health Coaching (Behavioral)

Experimental Condition 5

Experimental

Research participant receives the Core Components + UV Real-Time Alerts + Track Your Sun Protection + Health Coaching + Action Planning

Intervention: Action Planning (Behavioral)

Experimental Condition 5

Experimental

Research participant receives the Core Components + UV Real-Time Alerts + Track Your Sun Protection + Health Coaching + Action Planning

Intervention: Core Components (Behavioral)

Experimental Condition 6

Experimental

Research participant receives the Core Components + UV Real-Time Alerts + Track Your Sun Protection + Health Coaching

Intervention: UV Real-Time Alerts (Behavioral)

Experimental Condition 6

Experimental

Research participant receives the Core Components + UV Real-Time Alerts + Track Your Sun Protection + Health Coaching

Intervention: Track Your Sun Protection (Behavioral)

Experimental Condition 6

Experimental

Research participant receives the Core Components + UV Real-Time Alerts + Track Your Sun Protection + Health Coaching

Intervention: Health Coaching (Behavioral)

Experimental Condition 6

Experimental

Research participant receives the Core Components + UV Real-Time Alerts + Track Your Sun Protection + Health Coaching

Intervention: Core Components (Behavioral)

Experimental Condition 7

Experimental

Research participant receives the Core Components + UV Real-Time Alerts + Track Your Sun Protection + Action Planning

Intervention: UV Real-Time Alerts (Behavioral)

Experimental Condition 7

Experimental

Research participant receives the Core Components + UV Real-Time Alerts + Track Your Sun Protection + Action Planning

Intervention: Track Your Sun Protection (Behavioral)

Experimental Condition 7

Experimental

Research participant receives the Core Components + UV Real-Time Alerts + Track Your Sun Protection + Action Planning

Intervention: Action Planning (Behavioral)

Experimental Condition 7

Experimental

Research participant receives the Core Components + UV Real-Time Alerts + Track Your Sun Protection + Action Planning

Intervention: Core Components (Behavioral)

Experimental Condition 8

Experimental

Research participant receives the Core Components + UV Real-Time Alerts + Track Your Sun Protection

Intervention: UV Real-Time Alerts (Behavioral)

Experimental Condition 8

Experimental

Research participant receives the Core Components + UV Real-Time Alerts + Track Your Sun Protection

Intervention: Track Your Sun Protection (Behavioral)

Experimental Condition 8

Experimental

Research participant receives the Core Components + UV Real-Time Alerts + Track Your Sun Protection

Intervention: Core Components (Behavioral)

Experimental Condition 9

Experimental

Research participant receives the Core Components + UV Real-Time Alerts + Current Conditions + Health Coaching + Action Planning

Intervention: UV Real-Time Alerts (Behavioral)

Experimental Condition 9

Experimental

Research participant receives the Core Components + UV Real-Time Alerts + Current Conditions + Health Coaching + Action Planning

Intervention: Current Conditions (Behavioral)

Experimental Condition 9

Experimental

Research participant receives the Core Components + UV Real-Time Alerts + Current Conditions + Health Coaching + Action Planning

Intervention: Health Coaching (Behavioral)

Experimental Condition 9

Experimental

Research participant receives the Core Components + UV Real-Time Alerts + Current Conditions + Health Coaching + Action Planning

Intervention: Action Planning (Behavioral)

Experimental Condition 9

Experimental

Research participant receives the Core Components + UV Real-Time Alerts + Current Conditions + Health Coaching + Action Planning

Intervention: Core Components (Behavioral)

Experimental Condition 10

Experimental

Research participant receives the Core Components + UV Real-Time Alerts + Current Conditions + Health Coaching

Intervention: UV Real-Time Alerts (Behavioral)

Experimental Condition 10

Experimental

Research participant receives the Core Components + UV Real-Time Alerts + Current Conditions + Health Coaching

Intervention: Current Conditions (Behavioral)

Experimental Condition 10

Experimental

Research participant receives the Core Components + UV Real-Time Alerts + Current Conditions + Health Coaching

Intervention: Health Coaching (Behavioral)

Experimental Condition 10

Experimental

Research participant receives the Core Components + UV Real-Time Alerts + Current Conditions + Health Coaching

Intervention: Core Components (Behavioral)

Experimental Condition 11

Experimental

Research participant receives the Core Components + UV Real-Time Alerts + Current Conditions + Action Planning

Intervention: UV Real-Time Alerts (Behavioral)

Experimental Condition 11

Experimental

Research participant receives the Core Components + UV Real-Time Alerts + Current Conditions + Action Planning

Intervention: Current Conditions (Behavioral)

Experimental Condition 11

Experimental

Research participant receives the Core Components + UV Real-Time Alerts + Current Conditions + Action Planning

Intervention: Action Planning (Behavioral)

Experimental Condition 11

Experimental

Research participant receives the Core Components + UV Real-Time Alerts + Current Conditions + Action Planning

Intervention: Core Components (Behavioral)

Experimental Condition 12

Experimental

Research participant receives the Core Components + UV Real-Time Alerts + Current Conditions

Intervention: UV Real-Time Alerts (Behavioral)

Experimental Condition 12

Experimental

Research participant receives the Core Components + UV Real-Time Alerts + Current Conditions

Intervention: Current Conditions (Behavioral)

Experimental Condition 12

Experimental

Research participant receives the Core Components + UV Real-Time Alerts + Current Conditions

Intervention: Core Components (Behavioral)

Experimental Condition 13

Experimental

Research participant receives the Core Components + UV Real-Time Alerts + Health Coaching + Action Planning

Intervention: UV Real-Time Alerts (Behavioral)

Experimental Condition 13

Experimental

Research participant receives the Core Components + UV Real-Time Alerts + Health Coaching + Action Planning

Intervention: Health Coaching (Behavioral)

Experimental Condition 13

Experimental

Research participant receives the Core Components + UV Real-Time Alerts + Health Coaching + Action Planning

Intervention: Action Planning (Behavioral)

Experimental Condition 13

Experimental

Research participant receives the Core Components + UV Real-Time Alerts + Health Coaching + Action Planning

Intervention: Core Components (Behavioral)

Experimental Condition 14

Experimental

Research participant receives the Core Components + UV Real-Time Alerts + Health Coaching

Intervention: UV Real-Time Alerts (Behavioral)

Experimental Condition 16

Experimental

Research participant receives the Core Components + UV Real-Time Alerts

Intervention: UV Real-Time Alerts (Behavioral)

Experimental Condition 14

Experimental

Research participant receives the Core Components + UV Real-Time Alerts + Health Coaching

Intervention: Health Coaching (Behavioral)

Experimental Condition 16

Experimental

Research participant receives the Core Components + UV Real-Time Alerts

Intervention: Core Components (Behavioral)

Experimental Condition 14

Experimental

Research participant receives the Core Components + UV Real-Time Alerts + Health Coaching

Intervention: Core Components (Behavioral)

Experimental Condition 15

Experimental

Research participant receives the Core Components + UV Real-Time Alerts + Action Planning

Intervention: UV Real-Time Alerts (Behavioral)

Experimental Condition 15

Experimental

Research participant receives the Core Components + UV Real-Time Alerts + Action Planning

Intervention: Action Planning (Behavioral)

Experimental Condition 15

Experimental

Research participant receives the Core Components + UV Real-Time Alerts + Action Planning

Intervention: Core Components (Behavioral)

Experimental Condition 17

Experimental

Research participant receives the Core Components + Track Your Sun Protection + Current Conditions + Health Coaching + Action Planning

Intervention: Track Your Sun Protection (Behavioral)

Experimental Condition 17

Experimental

Research participant receives the Core Components + Track Your Sun Protection + Current Conditions + Health Coaching + Action Planning

Intervention: Current Conditions (Behavioral)

Experimental Condition 17

Experimental

Research participant receives the Core Components + Track Your Sun Protection + Current Conditions + Health Coaching + Action Planning

Intervention: Health Coaching (Behavioral)

Experimental Condition 17

Experimental

Research participant receives the Core Components + Track Your Sun Protection + Current Conditions + Health Coaching + Action Planning

Intervention: Action Planning (Behavioral)

Experimental Condition 17

Experimental

Research participant receives the Core Components + Track Your Sun Protection + Current Conditions + Health Coaching + Action Planning

Intervention: Core Components (Behavioral)

Experimental Condition 18

Experimental

Research participant receives the Core Components + Track Your Sun Protection + Current Conditions + Health Coaching

Intervention: Track Your Sun Protection (Behavioral)

Experimental Condition 18

Experimental

Research participant receives the Core Components + Track Your Sun Protection + Current Conditions + Health Coaching

Intervention: Current Conditions (Behavioral)

Experimental Condition 18

Experimental

Research participant receives the Core Components + Track Your Sun Protection + Current Conditions + Health Coaching

Intervention: Health Coaching (Behavioral)

Experimental Condition 18

Experimental

Research participant receives the Core Components + Track Your Sun Protection + Current Conditions + Health Coaching

Intervention: Core Components (Behavioral)

Experimental Condition 19

Experimental

Research participant receives the Core Components + Track Your Sun Protection + Current Conditions + Action Planning

Intervention: Track Your Sun Protection (Behavioral)

Experimental Condition 19

Experimental

Research participant receives the Core Components + Track Your Sun Protection + Current Conditions + Action Planning

Intervention: Current Conditions (Behavioral)

Experimental Condition 29

Experimental

Research participant receives the Core Components + Health Coaching + Action Planning

Intervention: Core Components (Behavioral)

Experimental Condition 19

Experimental

Research participant receives the Core Components + Track Your Sun Protection + Current Conditions + Action Planning

Intervention: Action Planning (Behavioral)

Experimental Condition 19

Experimental

Research participant receives the Core Components + Track Your Sun Protection + Current Conditions + Action Planning

Intervention: Core Components (Behavioral)

Experimental Condition 20

Experimental

Research participant receives the Core Components + Track Your Sun Protection + Current Conditions

Intervention: Track Your Sun Protection (Behavioral)

Experimental Condition 21

Experimental

Research participant receives the Core Components + Track Your Sun Protection + Health Coaching + Action Planning

Intervention: Action Planning (Behavioral)

Experimental Condition 20

Experimental

Research participant receives the Core Components + Track Your Sun Protection + Current Conditions

Intervention: Current Conditions (Behavioral)

Experimental Condition 20

Experimental

Research participant receives the Core Components + Track Your Sun Protection + Current Conditions

Intervention: Core Components (Behavioral)

Experimental Condition 21

Experimental

Research participant receives the Core Components + Track Your Sun Protection + Health Coaching + Action Planning

Intervention: Health Coaching (Behavioral)

Experimental Condition 21

Experimental

Research participant receives the Core Components + Track Your Sun Protection + Health Coaching + Action Planning

Intervention: Track Your Sun Protection (Behavioral)

Experimental Condition 21

Experimental

Research participant receives the Core Components + Track Your Sun Protection + Health Coaching + Action Planning

Intervention: Core Components (Behavioral)

Experimental Condition 22

Experimental

Research participant receives the Core Components + Track Your Sun Protection + Health Coaching

Intervention: Track Your Sun Protection (Behavioral)

Experimental Condition 22

Experimental

Research participant receives the Core Components + Track Your Sun Protection + Health Coaching

Intervention: Health Coaching (Behavioral)

Experimental Condition 22

Experimental

Research participant receives the Core Components + Track Your Sun Protection + Health Coaching

Intervention: Core Components (Behavioral)

Experimental Condition 23

Experimental

Research participant receives the Core Components + Track Your Sun Protection + Action Planning

Intervention: Track Your Sun Protection (Behavioral)

Experimental Condition 23

Experimental

Research participant receives the Core Components + Track Your Sun Protection + Action Planning

Intervention: Action Planning (Behavioral)

Experimental Condition 23

Experimental

Research participant receives the Core Components + Track Your Sun Protection + Action Planning

Intervention: Core Components (Behavioral)

Experimental Condition 24

Experimental

Research participant receives the Core Components + Track Your Sun Protection

Intervention: Track Your Sun Protection (Behavioral)

Experimental Condition 24

Experimental

Research participant receives the Core Components + Track Your Sun Protection

Intervention: Core Components (Behavioral)

Experimental Condition 25

Experimental

Research participant receives the Core Components + Current Conditions + Health Coaching + Action Planning

Intervention: Current Conditions (Behavioral)

Experimental Condition 25

Experimental

Research participant receives the Core Components + Current Conditions + Health Coaching + Action Planning

Intervention: Health Coaching (Behavioral)

Experimental Condition 25

Experimental

Research participant receives the Core Components + Current Conditions + Health Coaching + Action Planning

Intervention: Action Planning (Behavioral)

Experimental Condition 25

Experimental

Research participant receives the Core Components + Current Conditions + Health Coaching + Action Planning

Intervention: Core Components (Behavioral)

Experimental Condition 26

Experimental

Research participant receives the Core Components + Current Conditions + Health Coaching

Intervention: Current Conditions (Behavioral)

Experimental Condition 26

Experimental

Research participant receives the Core Components + Current Conditions + Health Coaching

Intervention: Health Coaching (Behavioral)

Experimental Condition 29

Experimental

Research participant receives the Core Components + Health Coaching + Action Planning

Intervention: Health Coaching (Behavioral)

Experimental Condition 29

Experimental

Research participant receives the Core Components + Health Coaching + Action Planning

Intervention: Action Planning (Behavioral)

Experimental Condition 26

Experimental

Research participant receives the Core Components + Current Conditions + Health Coaching

Intervention: Core Components (Behavioral)

Experimental Condition 27

Experimental

Research participant receives the Core Components + Current Conditions + Action Planning

Intervention: Current Conditions (Behavioral)

Experimental Condition 27

Experimental

Research participant receives the Core Components + Current Conditions + Action Planning

Intervention: Action Planning (Behavioral)

Experimental Condition 27

Experimental

Research participant receives the Core Components + Current Conditions + Action Planning

Intervention: Core Components (Behavioral)

Experimental Condition 28

Experimental

Research participant receives the Core Components + Current Conditions

Intervention: Current Conditions (Behavioral)

Experimental Condition 28

Experimental

Research participant receives the Core Components + Current Conditions

Intervention: Core Components (Behavioral)

Experimental Condition 30

Experimental

Research participant receives the Core Components + Health Coaching

Intervention: Health Coaching (Behavioral)

Experimental Condition 30

Experimental

Research participant receives the Core Components + Health Coaching

Intervention: Core Components (Behavioral)

Experimental Condition 31

Experimental

Research participant receives the Core Components + Action Planning

Intervention: Action Planning (Behavioral)

Experimental Condition 31

Experimental

Research participant receives the Core Components + Action Planning

Intervention: Core Components (Behavioral)

Experimental Condition 32

Experimental

Research participant receives the Core Components only

Intervention: Core Components (Behavioral)

Outcomes

Primary Outcomes

Feasibility: Retention Rates

Time Frame: Intervention period (weeks 2-9)

Retention rates will be calculated for the overall study and separately for each component. Feasibility target: \<=30% treatment drop-out (or lost to follow-up) in at-least one treatment component. Investigators will report feasibility in aggregate and by site.

Feasibility: Completion of Daily Assessment Week Surveys

Time Frame: 1-week bursts at baseline, post-intervention (2 months later) and 12 months post baseline.

Assessment completion will be calculated for daily surveys (a combination of MUSE and device logging) completed during each assessment week. Feasibility target: \>=80% completion. Investigators will report feasibility in aggregate and by site.

Feasibility: Completion of Pre-Assessment Week Surveys

Time Frame: 1-week bursts at baseline, post-intervention (2 months later) and 12 months post baseline.

Assessment completion will be calculated for the Pre-Assessment Week Survey (a combination of the Sun Habits Survey, Social Cognitive Theory Questions and Godin Leisure-Time Questionnaire) completed once at the start of each assessment week. Feasibility target: \>=80% completion. Investigators will report feasibility in aggregate and by site.

Feasibility: Weekly Device Wear

Time Frame: 1-week bursts at baseline, post-intervention (2 months later) and 12 months post baseline.

Device wear will be calculated for the UVR sensor and Actigraph (number of days worn more than 8 hours at each assessment week). Feasibility target: \>=80% completion. Investigators will report feasibility in aggregate and by site.

Unprotected Sun Exposure

Time Frame: 1-week bursts at baseline, post-intervention (2 months later), and 12 months post baseline.

Unprotected Sun Exposure is calculated based on a combination of self-report and sensor data. The Daily MUSE Inventory, will be used to assess sun exposure based on the outdoor activities that a participant completes. On this measure, participants first select the type, timing, and clothing worn by activity performed. Participants then report on applications of sunscreen, including time applied (or reapplied), body sites covered, and SPF. The UVR sensor will continually assess UVR dose during assessment weeks. The information from the Daily MUSE Inventory will be aligned with data from UVR sensors to generate, unprotected sun exposure, which is the UVR dose weighted by the proportion of body surface area exposed.

Secondary Outcomes

  • Feasibility: Response Rates to Intervention Components(Intervention period (weeks 2-9))
  • Sunburns(1-week bursts at baseline, post-intervention (2 months later), and 12 months post baseline.)
  • Usability, Burden, and Acceptability Self-Reports(Post-assessment week 2 (2.5 months later))

Investigators

Sponsor Class
Other
Responsible Party
Principal Investigator
Principal Investigator

Nabil Alshurafa

Principal Investigator

Northwestern University

Study Sites (2)

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