Microwave Ablation for Pulmonary Metastases From Colorectal Cancer

Not Applicable

Completed

• Conditions: Colorectal Cancer
• Interventions: Device: microwave ablation

• Registration Number: NCT02502630
• Lead Sponsor: The First People's Hospital of Changzhou

Brief Summary

(MWA) is the most recent development in the field of local ablative therapies. The aim of this study was to evaluate CT-guided percutaneous microwave (MW) ablation safety and efficacy in pulmonary metastases from colorectal cancer.

Detailed Description

From June 2010 to June 2015, 48 unresectable lesions in 32 patients with pulmonary metastases from colorectal cancer were selected for CT-guided microwave ablation. Patients were scheduled for a 1 and 3 month CT follow-up to evaluate lesion diameter.We retrospectively evaluated CT-guided percutaneous microwave (MW) ablation safety and efficacy in pulmonary metastases from colorectal cancer.

Study Timeline

• Study Start: 2010-06
• Primary Completion: 2015-06
• Study Completion: 2015-07
• Study First Submitted: 2015-07-15
• Study First Submitted QC: 2015-07-16
• Study First Posted: 2015-07-20
• Status Verified: 2016-08
• Last Update Submitted: 2016-08-11
• Last Update Posted: 2016-08-15

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 32

Inclusion Criteria

• Unresectable pulmonary metastases from colorectal cancer.
• diagnosis by CT, and confirmed by percutaneous puncture biopsy.
• Age range 18-70 years old.
• Eastern Cooperative Oncology Group performance status 0-1.
• Life expectancy of more than 3 months.
• Adequate organ function.

Exclusion Criteria

• Resectable lung metastases.
• Life expectancy less than 3 months
• Patients with cardiac pacemaker, cerebral aneurysm clips, implanted electronic instruments or other metal materials.
• Coagulopathy with platelet count less than 50000.
• Active infectious disease.
• Age below 18 years.
• Pregnancy of breastfeeding.

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: SINGLE_GROUP

Arm && Interventions

Group	Intervention	Description
Treated with microwave ablation	microwave ablation	Patients undergoing MWA for pulmonary metastases from colorectal cancer.

Primary Outcome Measures

Name	Time	Method
Overall Survival (OS)	one year

Secondary Outcome Measures

Name	Time	Method
Treatment related adverse events	Eight weeks