Homeopathic treatment of knee osteoarthritis
- Conditions
- Health Condition 1: null- Knee osteoarthritisHealth Condition 2: M179- Osteoarthritis of knee, unspecified
- Registration Number
- CTRI/2018/04/013395
- Lead Sponsor
- ational Institute of Homoeopathy Ministry of AYUSH Govt of India
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 128
1. Age 40-70 years
2. Both sexes
3. Diagnosed knee osteoarthritis as per American College of Rheumatology (ACR) clinical or radiographic classification criteria (sensitivity 91%; specificity 86%):
a) Knee pain
b) At least 1 of 3: age more than 50 yrs, stiffness less than 30 min, and crepitus on knee motion
c) Osteophytes on x-ray knee (AP/lateral view)
4. Patients already undergoing regular oral or topical analgesics or NSAID therapy for painful episodes of osteoarthritis, provided the medications are stopped completely at least 2 weeks prior study entry
5. Providing written informed consent
6. Literate patients; ability to read English and/or Bengali
1. Severe degeneration of knee joint with marked joint narrowing, varus, or valgus deformity of knee ( >12°), evidenced by imaging or other evidences and requiring surgical intervention
2. Non-ambulant patients
3. Self-reported joint disorders other than osteoarthritis (e.g., inflammatory joint disease, specific arthropathy, severe axis deviations or instabilities, joint or skin infections, joint prostheses of the lower limbs)
4. Intra-articular injections within 2 wk before study entry
5. Transplanted knees
6. Recent significant knee surgery within last 6 months
7. Patients who are too sick for consultation
8. Unwilling to take part and not giving consent to join the study
9. Unable to read patient information sheet
10. Diagnosed cases of unstable mental or psychiatric illness or other uncontrolled or life-threatening illness affecting quality of life
11. Pregnancy and lactation
12. Substance abuse and/or dependence
13. Self-reported immune-compromised state, and
14. Undergoing homeopathic treatment for any chronic disease within last 6 months
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Bengali version of the Knee injury and Osteoarthritis Outcome Score (KOOS) questionnaireTimepoint: At baseline, after 3 months, and after 6 months
- Secondary Outcome Measures
Name Time Method Five individual KOOS subscale scores â?? pain, other symptoms, activity of daily living (ADL), sport or recreation, and knee-related quality of life (QOL)Timepoint: At baseline, after 3 months, and after 6 months;Frequency of add-on Paracetamol and/or NSAIDs (oral/topical) useTimepoint: 6 months