Target Blood Pressure in patients with liver disease
Not Applicable
- Conditions
- Health Condition 1: null- Critically ill cirrhoticsHealth Condition 2: K746- Other and unspecified cirrhosis ofliver
- Registration Number
- CTRI/2017/07/009001
- Lead Sponsor
- Institute of liver and Biliary Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Open to Recruitment
- Sex
- Not specified
- Target Recruitment
- 228
Inclusion Criteria
Critically ill cirrhotics with septic shock
Exclusion Criteria
1) Patients with age less than 18 years
2) Severe known cardiopulmonary disease (structural or valvular heart disease, coronary artery disease, COPD)
3) Pregnancy
4) Chronic kidney disease on hemodialysis
5) Extremely moribund patients with an expected life expectancy of less than 24 hours
6) Failure to give informed consent from family members.
7) Hemodynamic instability requiring very high dose of vasopressors
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method SurvivalTimepoint: 28 days
- Secondary Outcome Measures
Name Time Method Duration of ICU/Hospital stayTimepoint: 3 months;Duration of mechanical ventilationTimepoint: 3 months;Incidence of intradialytic hypotension in patients undergoing Renal Replacement TherapyTimepoint: 3 months;Reversal of Acute Kidney InjuryTimepoint: Day 5;Reversal of shockTimepoint: Day 5