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临床试验/NCT06347549
NCT06347549已完成不适用

Diaphragmatic and Sternocleidomastoid Muscle Recruitment at Various Inspiratory Loads With and Without Breathing Instruction in Healthy Adults

Hong Kong Metropolitan University1 个研究点 分布在 1 个国家目标入组 62 人开始时间: 2024年4月8日最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
入组人数
62
试验地点
1
主要终点
Diaphragmatic thickening fraction

研究概览

简要总结

This is a cross-sectional obsessional study.

This study aims (1) to investigate the relationship between sternocleidomastoid muscle recruitment and diaphragm thickness fraction during increasing inspiratory resistance in healthy adults; (2) to compare diaphragmatic and sternocleidomastoid muscle recruitment patterns with and without a standard diaphragmatic breathing instruction with increasing inspiratory resistance in healthy adults.

Participants will be asked to breathe through a pressure threshold inspiratory loading device under different inspiratory resistances with and without a standard diaphragmatic breathing instruction. sternocleidomastoid muscle activity will be measured with surface electromyography, and diaphragm thickness will be assessed with ultrasonography.

详细描述

Upon arrival at the laboratory, eligible participants will first perform a standard spirometry lung function test. The maximum inspiratory pressure (MIP) will be determined with a pressure threshold inspiratory loading device (POWERbreathe, K2). Each participant will then be instructed to use the device to perform, in random order, 10 breaths at an inspiratory intensity of 30%, 40%, 50%, 60%, 70%, and 80% MIP. A rest period of 15 minutes will be allowed between each inspiratory pressure set of 10 breaths. Simultaneous surface electromyographic (sEMG) recording of the right sternocleidomastoid muscle and ultrasound of right diaphragmatic thickness will be conducted during each breath.

The entire recording procedure will be repeated on a separate day. During the repeat measurements, participants will be provided with specific breathing instruction to focus on the use of the diaphragm and to inhale air to the lower part of the chest. Practice trials will be conducted to ensure participant's understanding of diaphragmatic breathing.

研究设计

研究类型
Observational
观察模型
Case Crossover
时间视角
Cross Sectional

入排标准

年龄范围
18 Years 至 80 Years(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • Participants ≥18 years of age with normal health

排除标准

  • Pregnancy.
  • Participants with known cardiovascular, pulmonary, musculoskeletal or psychiatric disorders.
  • Participants with respiratory symptoms (from flu or other respiratory infection during the 2 weeks prior to measurements.
  • Participants can not cooperate the maximal inspiratory pressure measurement.

结局指标

主要结局

Diaphragmatic thickening fraction

时间窗: Through study completion, an average of 1 year

Diaphragmatic thickening fraction is determined by "(thickness of the diaphragm at end inspiratory - thickness at end expiratory)/thickness at end expiratory". Diaphragmatic thickness will be measured by ultrasonography.

次要结局

  • Muscle activation of the sternocleidomastoid muscle(Through study completion, an average of 1 year)
  • Perceived Exertion Borg scale(Through study completion, an average of 1 year)

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

LIU FANG

PhD student

Hong Kong Metropolitan University

研究点 (1)

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