Dietary Nitrate Supplementation in Stable Chronic Obstructive Pulmonary Disease (COPD): A Randomised Controlled Trial
Not Applicable
- Conditions
- Chronic obstructive pulmonary disease (COPD)Respiratory - Chronic obstructive pulmonary disease
- Registration Number
- ACTRN12611001088932
- Lead Sponsor
- Prof Don Campbell, Head of General Medicine
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot yet recruiting
- Sex
- All
- Target Recruitment
- 25
Inclusion Criteria
Patients with stable mild-moderate chronic obstructive pulmonary disease (FEV1 > 50% predicted).
Physically able to perform a six-minute walk test.
Exclusion Criteria
Acute exacerbation of COPD in the preceding month.
Long-term oxygen therapy.
Treatment with oral corticosteroids at the time of recruitment.
Treatment with beta-blockers.
A known diagnosis of ischaemic heart disease or heart failure.
Musculoskeletal disorders limiting exercise.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Improvement in endurance shuttle walk test performance.[2nd and 3rd session of exercise testing, compared to baseline testing.]
- Secondary Outcome Measures
Name Time Method Borg dyspnoea scores.[2nd and 3rd session of exercise testing, compared to baseline testing.]