Duodenal Jejunal Bypass for Type 2 Diabetes (DJBD)
Phase 1
- Conditions
- Diabetes Mellitus
- Registration Number
- NCT00487526
- Lead Sponsor
- Ferzli, George S., M.D. F.A.C.S.
- Brief Summary
Study the effect of Duodenal jejunal bypass on human adults with type 2 diabetes.
- Detailed Description
Adults non obese ( BMI less than 34 ) will undergo duodenal jejunal bypass. The Outcome measures: Blood Sugar, Insulin,HbA1c, CCK,Gastrin, GIP1and 2, Ghrelin, Cholesterol, Triglycerides,FFA, C-Peptide.
Recruitment & Eligibility
- Status
- UNKNOWN
- Sex
- All
- Target Recruitment
- 50
Inclusion Criteria
- Adults age 20-65
- Clinical diagnosis of type 2 diabetes
- Non obese with BMI less than 34.
- Oral agents or insulin to control T2DM.
- Inadequate control of diabetes as defined as HbA1c>/7.5
- Understanding of the mechanisms of action of the treatment
Exclusion Criteria
- Children with type 1 diabetes
- Obese with BMI over 34
- Coagulopathy
- Liver cirrhosis
- Unable to comply with study requirements, follow-up or give valid consent
- Currently pregnant
- Previous upper abdominal surgery
- Inabilty to tolerate general anesthesia
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- SINGLE_GROUP
- Primary Outcome Measures
Name Time Method control of type 2 diabetes in non obese adults two years
- Secondary Outcome Measures
Name Time Method CCK FFA,Cholesterol,Ghrelin,C-peptide,HbA1c,Gastrin,GIP,Triglycerides,Insulin 2 years
Trial Locations
- Locations (1)
Center for Advance Medicine Abel Gonzalez
🇩🇴Santo Domingo, Dominican Republic