Magnetic Resonance Imaging of Infrapatellar Fat Pad in Osteoarthritis and Controls
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 121
- 试验地点
- 1
- 主要终点
- Infrapatellar Fat Pad Volume in MRI
研究概览
简要总结
In this study, the investigators use the clinical documentation and imaging data of MRI to do research. Clinical subjects were divided into two groups: osteoarthritis patients and healthy controls without osteoarthritis. Differences of MRI data were studied between two groups.
详细描述
In this study, the investigators applied high precision MRI technique (with as less as a slice thickness of 0.35 mm and without inter-slice gap), and calculated not only the IPFP maximal sagittal area and IPFP volume, but also the quantitated signal, and compared the differences between healthy controls and osteoarthritis patients. This is an observational cross-sectional study without specific interventions to the subjects. MRI is a regular examination in our hospital. And all subjects are included for the reasons of osteoarthritis (need MRI) and healthy controls (pain but not osteoarthritis, also need MRI). The investigator does not assign specific interventions to the subjects of the study.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Control
- 时间视角
- Cross Sectional
入排标准
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Patients with clinical knee osteoarthritis;
- •The healthy controls who require MRI test.
排除标准
- •Contraindications to magnetic resonance imaging;
- •Rheumatoid arthritis patients;
- •Hemophilic arthritis;
- •Subjects who take non-steroidal anti-inflammatory drugs (NSAIDs);
- •Subjects who take lipid-lowering agents;
- •Subjects who have the history of knee trauma;
- •Subjects who have the history of knee operation;
- •Subjects who have the disease of musculoskeletal tumor near knee;
- •Subjects who have joint loose bodies.
结局指标
主要结局
Infrapatellar Fat Pad Volume in MRI
时间窗: collect the data within 24 hours after the subjects did the MRI
次要结局
未报告次要终点