Measuring the DNA Methylation Effects From COVID-19 Infection and COVID-vaccinations
试验速览
- 阶段
- 不适用
- 发起方
- 入组人数
- 60
- 试验地点
- 1
- 主要终点
- Methylation age clock testing
研究概览
简要总结
This is a retrospective non-randomized clinical study of 60 patients total to assess the effects of SARS-CoV-2 infection and the SARS-CoV-2 vaccination. This study will have 2 arms evaluating the epigenomes of patients pre and post-exposure to one of the interventions. The first arm of the study will analyze 40 patients' epigenomes whose DNA methylation was examined pre and post SARS-CoV-2 infection. The second arm of this study is analyzing 20 patients' epigenomes whose DNA methylation was examined pre and post-injection of the SARS-CoV-2 vaccine.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Retrospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Subjects that are healthy individuals and of any sex, ethnicity, and anyone above the age of 18 years old.
排除标准
- 未提供
结局指标
主要结局
Methylation age clock testing
时间窗: Change from baseline after COVID-19 mRNA vaccination
The DNA clocks that will be used to precisely measure aging is TruAge Biological Age test, which estimates biological age vs. chronological age
次要结局
- Overall state of health(Change from baseline after COVID-19 mRNA vaccination)