In-Hospital Individualized Prescriptive Exercise Intervention for Acute Leukemia Patients Undergoing Chemotherapy
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 10
- 试验地点
- 2
- 主要终点
- Effects of an individualized prescriptive exercise intervention
研究概览
简要总结
RATIONALE: An individualized exercise program may be effective in lessening fatigue and depression and improving quality of life in patients undergoing chemotherapy for leukemia.
PURPOSE: This clinical trial is studying how well individualized exercise programs work in patients receiving chemotherapy for newly diagnosed acute or relapsed myeloid leukemia or lymphoblastic leukemia.
详细描述
OBJECTIVES:
Primary
- Determine the effects, in terms of fitness and blood parameters, fatigue levels, and quality of life, of an individualized prescriptive exercise intervention in patients with newly diagnosed acute or relapsed myeloid or lymphoblastic leukemia undergoing chemotherapy.
Secondary
- Determine the feasibility of developing an exercise program for these patients.
- Assess the changes in cardiovascular endurance, muscular strength, selected blood parameters, and response of inflammatory proteins to exercise in these patients.
- Evaluate fatigue, depression, and quality of life of these patients.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Supportive Care
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 60 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •DISEASE CHARACTERISTICS:
- •Newly diagnosed acute or relapsed myeloid or lymphoblastic leukemia
- •Currently receiving re-induction therapy or designated for chemotherapy treatment
- •Expected hospital stay of 3-4 weeks or longer
- •Participation in the study must be approved by the physician directly responsible for the patient's care while at University of North Carolina Hospitals
- •PATIENT CHARACTERISTICS:
- •No condition that would compromise the patient's ability to participate in the exercise rehabilitation program, including any of the following:
- •Immune deficiency
- •Acute or chronic bone, joint, or muscular abnormalities
- •Acute or chronic respiratory disease
- •Cardiovascular disease
- •PRIOR CONCURRENT THERAPY:
- •See Disease Characteristics
排除标准
- 未提供
结局指标
主要结局
Effects of an individualized prescriptive exercise intervention
时间窗: 6 weeks
All patients will participate in an individualized prescriptive exercise intervention 3 to 4 times per week (depending on the physical status of each patient during each week) for a period of 6 weeks. The exercise intervention will begin on week 1 of the study, the day after the first battery of initial assessments is concluded. Each exercise session will be divided into two bouts. One bout will be administered in the morning and the second one late in the afternoon
次要结局
- Number of subjects experiencing fatigue, depression, and quality of life issues(6 weeks)