Interaction of malignant cells and factors influencing tumour microenvironment

Recruiting

• Conditions: C92; C90.0; C81; C85; C96.8; Myeloid leukaemia; Multiple myeloma; Hodgkin lymphoma; Other and unspecified types of non-Hodgkin lymphoma; Histiocytic sarcoma

• Registration Number: DRKS00034065
• Lead Sponsor: niversitätsklinikum Schleswig-Holstein, Campus Lübeck

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2024-06-06
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 228

Inclusion Criteria

Cancer patients providing consent

Exclusion Criteria

Patients not providing consent and minors

Study & Design

• Study Type: observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Determine if the tissue surrounding tumour cells exhibits a higher mutation rate compared to non-infiltrated tissue

Secondary Outcome Measures

Name	Time	Method
Exploring the factors underlying the heightened mutation rate in adjacent tissue, encompassing genetic, metabolic, and proteomic changes. Additionally, the correlation between mutation rates in the stroma and patients' prognosis and outcomes will be investigated.