Effect of Methylphenidate on understanding intentionality in ADHD childre
Phase 4
Recruiting
- Conditions
- Attention-deficit hyperactivity disorder.Attention-deficit hyperactivity disorders
- Registration Number
- IRCT20201103049254N1
- Lead Sponsor
- Tehran University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- Male
- Target Recruitment
- 20
Inclusion Criteria
ADHD diagnosis according to Diagnostic and Statistical Manual of Mental Disorders, 5th Edition
Male sex
Age 8-12 years
IQ more than 90 according to Wechsler Intelligence Scale
Exclusion Criteria
Major psychiatric disorders
Neurologic disorders
Major medical disorders
Taking medications that affect the central nervous system
substance abuse
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Changes in the activity of brain regions related to the undrestanding intentionality. Timepoint: Before, and six weeks after starting the treatment with Methylphenidate. Method of measurement: Fanctional magnetic resonance brain imaging (fMRI).
- Secondary Outcome Measures
Name Time Method Ability of response inhibition. Timepoint: Before and six weeks after starting the treatment with Methylphenidate. Method of measurement: Stop-Signal task by Cambridge Neuropsychological Test Automated Battery (CANTAB).;Severity of core symptoms of attention deficit-hyperactivity disorder. Timepoint: Before and six weeks after starting the treatment with Methylphenidate. Method of measurement: Conners’ Parent Rating Scale (Questionnaire).;The effects of symptoms on behavior in terms of family, education, social and psychological. Timepoint: Before and six weeks after starting the treatment with Methylphenidate. Method of measurement: Children’s Global Assessment Scale.