Effectiveness and safety of oral misoprostol Vs intravaginal PGE2 (Dinoprostone) for pre-induction cervical ripening in women with uncomplicated, singleton, post dated pregnancies: a randomized controlled study.

Phase 4

• Conditions: Induction of labour

• Registration Number: SLCTR/2021/022
• Lead Sponsor: one

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Completion: 2022-02-15
• Last Update Posted: 20 August 2024

Recruitment & Eligibility

• Status: Complete: follow up complete
• Sex: Not specified
• Target Recruitment: Not specified

Inclusion Criteria

•Nulliparous pregnant women
•In a singleton pregnancy
•At 40 weeks and 5 days of gestation
•Fetus in cephalic presentation with intact membranes
•Modified bishop score(MBS) of < 5
•Not having any contraindications for vaginal delivery

Exclusion Criteria

•past caesarian delivery
•history of myomectomy
•hypersensitivity to misoprostol
•pregnancy induced hypertension
•gestational diabetes mellitus
•multiple pregnancies

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
To compare the number of women who establish spontaneous onset of labor (SOL) [Period of gestation - 40 weeks+6 days of gestation following the intervention at 40 weeks +5 days of gestation]<br>To compare the number of women who do not establish SOL ,but become favorable for induction of labor(IOL) with modified Bishops Score (MBS) ?7. [Period of gestation 40 weeks+6 days of gestation following the intervention at 40 weeks +5 days of gestation]<br>To compare the number of women who do not establish SOL and who are not favorable for IOL following 24 hours of the intervention. [Period of gestation 40 weeks+6 days of gestation following the intervention at 40 weeks +5 days of gestation]<br>To compare the intervention to delivery time in those who establishes SOL following interventions. [Period of gestation 40 weeks+6 days ]<br>